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The omnipresence of DOTA derivatives in 68Ga-PET arose from its success in other imaging applications (MRI and optical imaging with lanthanides) and its ability to provide an acceptable labelling profile and sufficient complex stability with 68Ga (Notni et al. 2011; Boros et al. 2010).
If only one anchoring receptor can provide sufficient complex stability the recruitment of a variety of low affinity receptor chains into signaling complexes might be possible.
A total of one to three selective bases were found to provide a sufficient complex pattern for the DNA polymorphism analysis.
Binding of a ligand to a single high affinity receptor chain functioning as anchoring molecule and providing sufficient complex stability allows the subsequent formation of signaling competent complexes.
Using a 4-fold excess of Prx1 over p66CH2CB to ensure sufficient complex formation, however, induced mitochondrial rupture even in absence of p66CH2CB (data not shown), making this assay incompatible with Prx1.
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Of these, 1100 had sufficient and complex flanking sequences for PCR primer design.
Although 2D projections of an evolving system can provide insightful information, this tool might not be sufficient if complex structures are present or high density sensitivity is required.
In cases of chronic injury, however, TFCC-repair alone is not sufficient, and complex restoration of DRUJ stability with tissue reconstruction is necessary.
For the even-numbered passes in route C, however, the simple shear deformation is not sufficient; the complex and inhomogeneous deformation captured by FE simulations is important for reproducing the retained shear texture.
This suggests that 20 nt long complementarities between the guide (EL9-11) and its target RNA are sufficient for complex formation.
At a very low ARNT concentration, there is no sufficient HIF ARNT complex, and therefore the degradation is less efficient.
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