substantially more potent

USAGE SUMMARY

The phrase "substantially more potent" is correct and usable in written English.
It can be used when comparing the effectiveness or strength of two or more substances, ideas, or actions, indicating a significant difference in potency. Example: "The new formula is substantially more potent than the previous version, leading to better results in clinical trials."

✓ Grammatically correct

Science

News & Media

Human-verified examples from authoritative sources

Exact Expressions

17 human-written examples

As shown in Table 2, the second series of vibralactone derivatives was substantially more potent than the first series.

Natural Products and Bioprospecting

This series represents a significant improvement on previous classes of compounds, being substantially more potent and largely retaining activity in the presence of serum.

Bioorganic & Medicinal Chemistry

Last, the new N1 C7 annulated derivatives presented herein are substantially more potent than their respective N1 C2 annulated counterparts, previously reported.

European Journal of Medicinal Chemistry

The anti-viral and anti-proliferative actions of IFN-α were substantially more potent against WISH and Daudi cells than 293 and RPMI 1788 cells, respectively.

Journal of Molecular Biology

While 34 is substantially more potent than cocaine as a DAT inhibitor, it is approximately four times less potent than cocaine in mimicking the discriminative stimulus properties of cocaine in rat.

Bioorganic & Medicinal Chemistry

Comparison of the cytotoxicity of KS119 in cultured cells lacking O6-alkylguanine-DNA alkyltransferase (AGT) to an agent such as Onrigin™, which through base catalyzed activation produces the same critical DNA G-C cross-link lesions by the generation of 90CE, indicates that KS119 is substantially more potent than Onrigin™ under conditions of oxygen deficiency, despite being incompletely activated.

Biochemical Pharmacology

Human-verified similar examples from authoritative sources

Similar Expressions

43 human-written examples

A strength of the computational screen was its prioritization of potent molecules, often substantially more so than those found empirically, and its ability to highlight chemotypes unexplored empirically.

ACS Chemical Biology

these agents are much more toxic (MMAE is 200 times more potent than vinblastine) [ 139], substantially limiting their clinical utility.

Drugs

RTX is a less potent TS inhibitor than CB3717 but exhibits substantially greater RFC uptake and metabolism to polyglutamates, leading to more potent anti-tumor effects in vitro and in vivo.

Cancer Biology and Therapy

Thus, while multivalent KLA polymers are more potent than KLA peptides, these materials can be substantially improved by designing next generation materials with improved cellular internalization and mitochondrial targeting efficiency.

Journal of Controlled Release

Although structurally different, both CRX-547 and dLOS act as a comparable or even more potent activator of human monocytes and dentritic cells with substantially reduced production of proinflammatory mediators associated with the MyD88 pathway.

Biological Reviews

Expert writing Tips

Best practice

When comparing two or more substances or strategies, use "substantially more potent" to clearly communicate a significant difference in effectiveness. For instance, in scientific writing, this phrase can emphasize the improved efficacy of a new compound over an existing one.

Common error

Avoid using multiple intensifiers with "potent". Phrases like "very substantially more potent" can sound redundant and weaken the impact of your statement. Choose one strong intensifier for clarity.

Linguistic Context

The phrase "substantially more potent" functions as an adjectival modifier, typically used to describe a noun by indicating a significant increase in its effectiveness or strength compared to something else. Ludwig AI confirms its correct and usable nature.

Expression frequency: Common

Frequent in

Science

75%

News & Media

15%

Formal & Business

10%

Less common in

Encyclopedias

0%

Wiki

0%

Reference

0%

Ludwig's WRAP-UP

The phrase "substantially more potent" is used to clearly express that something is significantly more effective or powerful than something else. As Ludwig AI confirms, it is a correct and usable phrase in written English. It is commonly found in scientific and formal contexts to emphasize a noticeable difference in efficacy or strength. When using the phrase, it's important to avoid redundancy by using only one intensifier. Consider alternatives like "significantly more effective" or "considerably stronger" to vary your writing while maintaining clarity and precision.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

substantially more powerful

Synonymous, simply uses "powerful" instead of "potent".

significantly more effective

Emphasizes the degree of effectiveness rather than pure potency.

far more effective

Highlights the difference of effectiveness.

considerably stronger

Focuses on the strength aspect, often used in physical or metaphorical contexts.

much more effective

Synonymous, it's a shorter way to highlight effectiveness difference.

markedly more powerful

Highlights the power or impact, suggesting a noticeable difference.

considerably more effective

Highlights effectiveness with different adverb.

noticeably more efficacious

A more formal and technical term for effectiveness, indicating a clear improvement.

distinctly more vigorous

Suggests increased energy or intensity, suitable for describing processes or actions.

appreciably more intense

Highlights the degree of intensity, indicating a tangible increase in effect.

FAQs

How can I use "substantially more potent" in a sentence?

Use "substantially more potent" to compare the effectiveness of two things, emphasizing a significant difference. For example: "The new drug is "substantially more potent" than the previous version".

What are some alternatives to "substantially more potent"?

Alternatives include "significantly more effective", "considerably stronger", or "markedly more powerful" depending on the specific context.

Is it correct to say "very substantially more potent"?

While grammatically correct, "very substantially more potent" can be redundant. Using just ""substantially more potent"" often provides sufficient emphasis.

What is the difference between "more potent" and "substantially more potent"?

"More potent" indicates a higher degree of effectiveness, while ""substantially more potent"" emphasizes that the difference in effectiveness is significant and noticeable.