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Exact(17)
One of the main reasons is the extraordinary recombination landscape in the variety bisporus causing substantial linkage drag.
However, substantial linkage disequilibrium within this region means that functional data are needed to determine the causal variant.
As a result, introgression breeding is hampered by substantial linkage drag, and QTL mapping is limited to the assignment of QTLs to chromosomes.
We observed substantial linkage disequilibrium (LD) between Vmn1r67 and Abpa27, a mouse salivary androgen-binding protein gene that encodes a proteinaceous pheromone (ABP) capable of mediating assortative mating, perhaps in conjunction with its bound small lipophilic ligand.
Overlap between the two cohorts was minimal for substantial linkage signals.
The region exhibits substantial linkage disequilibrium encompassing both the IL2 and IL21 genes.
Similar(43)
However, substantial LD requires strong linkage, especially for the prediction of unrelated individuals, and thus dense marker genotyping.
Our results indicate a substantial probability of linkage to chromosome 1, which had been previously overlooked; our findings also provide a further characterization of the possible parent-of-origin effects at the 17q11 locus that were previously described in this sample.
Substantial improvement in linkage to HIV care for TB and VCT patients was observed in more recent years in this study and yet this was not accompanied by improvements in linkage to ART.
None of our scans provided substantial evidence for linkage to FOXO3 on chromosome 6, probably because of the relatively small effect sizes conferred by SNPs at that locus [13] [18].
The markers contributing to the positive relationship between heterozygosity and breeding success were found to be located on different chromosomes, but there was a substantial amount of linkage disequilibrium in the population, indicating that the markers are reflecting heterozygosity over relatively wide genomic regions.
Related(20)
crucial linkage
essential linkage
major linkage
enormous linkage
noticeable linkage
appreciable linkage
large linkage
remarkable linkage
fundamental linkage
notable linkage
important linkage
huge linkage
substantial grievance
substantial dispute
substantial break
substantial neglect
substantial traffic
substantial effectiveness
substantial upgrade
substantial credit
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