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The most notable linkage was to chromosome 3p14.1.
Targeted resequencing near four association peaks with the most notable linkage disequilibrium provides further support of the role(s) of these regions in the genetic control of sorghum seed size and identifies two candidate causal variants with nonsynonymous mutations.
In some studies, notable linkage signals have been seen at two or three chromosome regions in the same family [ 11- 16] 16], which by chance would have a low probability [ 15].
The absence of notable linkage peaks in the remaining families conforms to a polygenic model with frequent alleles, sometimes cosegregating and sometimes being replaced by variants of different lineage or of other genes.
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For the recessive model, the most notable evidence of linkage occurred at 6p12.3 (HLOD = 2.64).
One notable area where the linkage between regulation and health outcomes has been made is in lead abatement.
It is notable that the S1 R2 linkage conformations lie within regions predicted computationally to have the highest energies (Fig. 4), which may represent either a problem with the structure or (if genuine) may account for the low binding affinity.
It is notable that the RFLP genetic linkage map by Jan et al. (1998) included 20 linkage groups, which is three more than the 17 haploid chromosome number of cultivated sunflower.
Some notable candidate genes within the linkage region include pro-opiomelanocortin (POMC), adiponectin (ADIPOQ), melanocortin receptor 4 (MC4R), and peroxisome proliferator-activated receptor γ (PPARγ).
Fourth, a relatively recent trend particularly notable in China and India is growing international linkages of domestic firms to advance innovative R&D activities.
A meta-methoxy group on the pyridyl ring and a gem-dimethyl methyl linkage afforded compound 10 with notable in vitro antiviral activity against HIV-1 viral strains with reduced susceptibility to the clinically available PIs. Compound 10 also demonstrated favorable in vivo pharmacokinetics in animal models.
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CEO of Professional Science Editing for Scientists @ prosciediting.com