Sentence examples for substantial less from inspiring English sources

Whereas the Tic- and Aba multimers proved to be dual and balanced δ/μ antagonists, as determined by the functional [S35]GTPγS binding assay, the dimerization of potent Aia-based 'parent' ligands unexpectedly resulted in substantial less efficient receptor binding and non-active dimeric compounds.

Thus, substantial less vaccine preparation is needed for the induction of protective immunity in mice.

The response rate of 43% with a median duration of response of 8 months observed in our study is in line with the results reported in the other studies with cisplatin and paclitaxel however with substantial less toxicity.

Although the absolute amount of these excreted substances in the carbon balance is not substantial (less than 5%), linking their accumulation dynamics to μ (or metabolic routes) is relevant for acknowledging the potential imbalance between pyrimidine metabolism, carbon re-consumption and ATP spilling.

While knowledge on factors affecting personal dignity of patients nearing death is quite substantial, far less is known about how patients living with a serious disease understand dignity.

Didn't we have anything more substantial, and less self-denigrating to talk about?

The median income in Dallas ― $43,359 ― is a substantial $12,292 less than the ideal income needed to live comfortably there.

For crown radius, the predicted variation, though substantial, was less than observed.