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Interestingly, the effects induced by these microparticles on the formation of capillary-like structures, expression of adhesion molecules, and pro-angiogenic factors are reversed after silencing of the Sonic Hedgehog (Shh) morphogen pathway.
And deeper understanding of their structures, expression profiles, interactions and functional diversity will be essential for our study in the detailed cellular processes mediated by WD40 proteins.
There are many biological data types - the most common include sequence data (nucleotide or protein), molecular structures, expression data, and functional annotations.
The next field provided a filter based on the following: Name/Annotation, Features, Structures, Expression, Antigenicity, Phylogenetic distribution, Essentiality, Validation data, Druggability, Assayability, and Bibliographic references.
The data available for biological systems are diverse in nature and include various types such as sequences, structures, expression data, interactions, pathways, systems data, phenotype(s) and population data [ 1].
The LEA protein classification proposed by Dure [ 4] and Bray [ 11] was recently revised by Wise [ 12] on the basis of the Kyte and Doolitle hydrophobicity metric, predicted secondary structures, expression patterns and sequence features.
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Extensive resequencing identified several nonsynonymous mutations, and the detected effects on TGR5 structure, expression and function provide valuable insight into the structural biology of the receptor.
When it functions normally, all is well, but if its structure, expression or function is altered, some form of cancer results.
Structure, expression, and function of both types of peptidase-complex in P. falciparum are presently unknown.
(JPEG 2 MB) 40529_2014_9055_MOESM4_ESM.tiff Additional file 4: Figure S3.: Genomic structure, expression levels and morphology of AtBS14b knock-out mutants.
Instead, non-conserved miRNAs must be proven using a combination of detailed analyses of their sequence, biogenesis, secondary structure, expression patterns, and silencing functions.
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