Sentence examples for striking defects from inspiring English sources

Conspicuously, dnrx null mutants display striking defects in synaptic ultrastructure, with the presence of detachments between pre- and postsynaptic membranes, abnormally long active zones, and increased number of T bars.

The embryonic Rap1 cKO mouse lens exhibited striking defects including loss of E-cadherin and ZO-1-based cell−cell junctions, disruption of paxillin and β1-integrin-based cell adhesive interactions along with abnormalities in cell shape and apical−basal polarity of epithelium.

The embryos have striking defects in caudal specification, limb patterning and axial skeleton formation.

Ablation of p120 results in striking defects in cell-cell adhesion and ameloblast morphology.

Depletion of these genes causes striking defects in the cell envelope, but not those observed following inhibition of σE [28], [51] [55].

For example, the authors show very striking defects in nucleolar organization.

A more striking defect in Hb expression was the nearly complete loss of posterior expression.

The most striking defect was observed in the developing liver, occupying only a small fraction of the abdominal areas (Fig. 2C and D).

IκBαΔNTg mice exhibited a striking defect in thymic STAT5a activation [70], and NF-κBSSAA/SSAA Knock-in mice, expressing a p105 mutant resistant to signal-induced degradation, also displayed a IL-2R signaling defect in peripheral T cells [56].

We observed a striking defect in the ability of the Q169 mutants to incorporate the second nucleotide, which corresponds to the second G in the extension product 5'-GGGTTAG-3'.

Another striking defect was also observed: large bundles of axons exiting the CNS, often extending beyond the CNS/PNS boundary ([Figure 1E, F] arrows) (herein designated AEP, Axons Exiting to Periphery).