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We can only speculate that such discrepancy in the pattern of arteriolar bed reorganization within the septum as opposed to the LV free wall of the female post-MI heart, in comparison to males, might be caused by a variety of factors, including the regional difference in wall stress [ 41] or temporary composition of growth-stimulating milieu [ 6].
Ward argues in a paper published in The International Journal of Cultural Policy, that while the council's strategy of arts-led regeneration has stimulated "a local milieu of artistic and cultural activity", it has failed to support local artists, which risks undermining the sustainability of the arts scene.
The hypoxic milieu stimulates secretion of profibrotic signals from tubular, interstitial and endothelial cells resulting in accumulation of fibrotic tissue [ 40].
For instance, uric acid microcrystals, which form upon release of the molecule to the sodium-rich extracellular milieu, stimulate dendritic cell maturation (Shi et al., 2003).
However, stimulation of chondrocytes with increased dosages of TNF-β resulted in an almost twofold increase in the adherence of T lymphocytes, demonstrating the active role that chondrocytes may play during RA in retaining lymphocytes in the joint, thus supporting an inflammatory milieu and stimulating ongoing inflammation.
For establishment of a proinflammatory milieu , we stimulated the cells with TNF-alpha (tumor necrosis factor-alpha) to activate proinflammatory pathways [ 31].
To mimic the in vivo milieu , we stimulated cells with cerebrospinal fluid from patients found to have no neurological disease and platelet derived growth factor BB (PDGF-BB), a known mitogen for meningioma cells [ 19, 20, 23].
Tumor-derived versican (a proteoglycan which sequesters chemokines and acts as a chemo-attractant for inflammatory cells in the tumor milieu ) can stimulate resident macrophages to secrete IL-6 and TNF-α in a TLR-2 dependent manner [ 26].
Expression of pro-inflammatory chemokines facilitates a chronic inflammation process and helps establish a favorable tumor milieu , which stimulates tumor proliferation and invasion via their receptors on tumor cells [ 20, 21].
This is possibly because the inflammatory mechanisms are extremely stimulated by the diabetic milieu or the β-cell dysfunction, and insulin resistance is more severe and less reversible by extended duration of diabetes as explained by Luo et al. [ 17].
Hence, cardiac milieu appears to stimulate proliferation but does not affect differentiation of skeletal myoblasts.
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The phrase "stimulating milieu" functions as an adjective-noun combination , where "stimulating" modifies the noun "milieu". This phrase typically describes an environment or setting that encourages or enhances activity, creativity, or intellectual engagement.
Expression frequency: Missing
