Sentence examples for smile down from inspiring English sources

She'd smile down at them.

He wanted to look at someone that way, to smile down at his own child.

"I think Charlotte can smile down now, knowing they solved this," Ms. Fauntleroy said.

Kozelek hangs on each word like a kid on the verge of tears: "Fill the void in me now, smile down on me".

The richness of the sauce and the tenderness of the meat momentarily shock me to silence as the inscrutable Fayssal and his jovial dad smile down at me.

Al Green, Roy Orbison and Elvis Presley smile down from restaurant wall posters, while hotels sport saxophone sculptures and staircases shaped like a piano keyboard.

These results suggest that SMILE down-regulation sensitizes cells to ER stress.

SMILE down-regulation and/or Bortezomib treatment induced dramatic ER enlargement and features of cellular injury.

Moreover, our DNA chip analysis revealed that SMILE down-regulation in HeLa cells affects the secretory pathway as well as vesicle-mediated transport (GO 0045045 and GO 0016192).

In contrast, SMILE down-regulation induced ER hypertrophy associated with a reduction of free ribosomes as compared to control cells (Fig. 4A and B), suggesting that down-regulation of SMILE affects ER function.

In order to determine whether there is a direct link between SMILE down-regulation and ER stress, we further tested XBP-1 expressinn in HeLa cells transfected with SMILE siRNA and treated 6 h with 20 nM Bortezomib.