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Justyna Jupowicz-Kozak

CEO of Professional Science Editing for Scientists @ prosciediting.com

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significant validation of

Grammar usage guide and real-world examples

USAGE SUMMARY

The phrase "significant validation of" is correct and usable in written English.
It can be used when discussing the confirmation or support of a theory, idea, or finding that holds considerable importance or impact. Example: "The study provided significant validation of the hypothesis that regular exercise improves mental health."

✓ Grammatically correct

Science

News & Media

Human-verified examples from authoritative sources

Exact Expressions

16 human-written examples

A total of 1,249 predicted targets were identified in these six modules, and 229 of them were validated through data from chromatin immunoprecipitation (ChIP) experiments [ 55- 57], providing a significant validation of the bio-informatic predictions (hypergeometric test; P = 7.73E-12; Methods).

Forbidden Technologies said the agreement gives it access to Microsoft's sales force and a new sales channel, as well as representing a significant validation of its technology.

However, no significant validation of this practice is to be found in the literature.

And sharing a piece of content is a significant validation of that thing: you're putting it out to all of your friends, and saying this is something you should spend your time on," he said.

And in perhaps the most significant validation of morning's position as the hot place to work at a network, NBC's top entertainment programmer, Jeff Zucker, took over as president of NBC Entertainment after dominating morning television when he ran "Today".

News & Media

The New York Times

Significant validation of the model has been possible using CREAM data flying onboard Concorde during the September/October 1989 events.

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Human-verified similar examples from authoritative sources

Similar Expressions

44 human-written examples

Moreover, the findings that are emerging from recent array comparative genomic hybridization studies indicate that significant validations of both controls and patient populations will be required to make phenotype-genotype interpretations in a clinical context.

Nonetheless, the high proportion of binders observed provides significant validation for the efficiency of this approach.

Science

Plosone

A significant validation criterion of our approach was to analyze modules in terms of protein complexes they contain.

Since 14 of the 23 genes are already known to be reactive to Insig1, these results represent a highly significant validation success of NEO; using the 23388 genes on the array and assuming that there are 200 known genes downstream of Insig1 (a conservative estimate), the Fisher exact p-value of validation success is p = 1.0 × 10-13.

These technologies are expensive and require significant validation, due to the enormous amount of data generated from microarray and high-throughput genome analysis.

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Expert writing Tips

Best practice

When using "significant validation of", ensure that the validation genuinely strengthens the claim or theory being presented. Quantify the significance whenever possible to enhance credibility.

Common error

Avoid using "significant validation of" for minor or incremental confirmations. Reserve this phrase for instances where the validation has a substantial impact on the field or subject matter.

Antonio Rotolo, PhD - Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Antonio Rotolo, PhD

Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Source & Trust

82%

Authority and reliability

4.1/5

Expert rating

Real-world application tested

Linguistic Context

The phrase "significant validation of" functions as a noun phrase that describes the confirmation or support of something, with the added emphasis that this confirmation is important or has a considerable impact. This is consistent with the examples provided by Ludwig.

Expression frequency: Uncommon

Frequent in

Science

70%

News & Media

20%

Wiki

10%

Less common in

Formal & Business

0%

Encyclopedias

0%

Reference

0%

Ludwig's WRAP-UP

In summary, the phrase "significant validation of" is a grammatically correct and usable expression in English that serves to highlight the importance and strength of a confirmation or support. According to Ludwig, it is commonly found in scientific and news media contexts, lending itself to formal and professional registers. When using this phrase, ensure the validation truly warrants the 'significant' descriptor and quantify the significance where possible. While alternatives like "substantial confirmation of" or "meaningful support for" exist, they may not always fully capture the original phrase's intended impact. Steer clear of overusing the phrase for minor confirmations to maintain its true meaning and impact.

More alternative expressions(6)

Phrases that express similar concepts, ordered by semantic similarity:

substantial confirmation of

Replaces "significant validation" with "substantial confirmation", emphasizing the confirmatory aspect but with a different adjective.

meaningful support for

Uses "meaningful support" to convey the idea of important backing or evidence, changing both the adjective and noun.

strong corroboration of

Employs "strong corroboration" to highlight the reinforcing nature of the validation, offering a more formal tone.

powerful endorsement of

Substitutes "significant validation" with "powerful endorsement", suggesting a strong and positive affirmation.

considerable verification of

Replaces "significant" with "considerable" and "validation" with "verification", keeping the core meaning intact but altering the phrasing.

noteworthy substantiation of

Uses "noteworthy substantiation" to indicate that the confirmation is both significant and has been proven.

major affirmation of

Substitutes with "major affirmation" suggesting a strong statement of truth or belief, rather than empirical validation.

important confirmation of

Uses "important confirmation" to express that something is crucial, but the phrase lacks the emphasis of strength that "significant" provides.

evident justification for

Replaces "validation" with "justification", which indicates a reason is being defended by evidence, shifting the emphasis from the validation itself.

remarkable proof of

Substitutes "significant validation" with "remarkable proof", highlighting the conclusiveness of the evidence, adding an element of surprise.

FAQs

How can I use "significant validation of" in a sentence?

Use "significant validation of" to describe a situation where something has been confirmed or supported in a way that has substantial importance or impact. For example, "The clinical trial provided "significant validation of" the drug's effectiveness".

What are some alternatives to "significant validation of"?

You can use alternatives like "substantial confirmation of", "meaningful support for", or "strong corroboration of" depending on the specific context and nuance you wish to convey. Each phrase offers a slightly different shade of meaning.

Is "significant validation of" appropriate for informal writing?

While grammatically correct, "significant validation of" leans towards a more formal tone. In informal contexts, consider using simpler phrases like "really proves" or "strongly supports".

What makes validation "significant"?

Validation is considered "significant" when it provides strong evidence, has broad implications, or substantially changes understanding of a particular subject. It goes beyond simple confirmation and offers a noteworthy level of support.

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Source & Trust

82%

Authority and reliability

4.1/5

Expert rating

Real-world application tested

Most frequent sentences: