significant predisposition to

USAGE SUMMARY

The phrase "significant predisposition to" is correct and usable in written English.
It can be used when discussing a strong tendency or inclination towards a particular behavior, condition, or outcome. Example: "The study revealed a significant predisposition to anxiety among individuals with a family history of mental health issues."

✓ Grammatically correct

Science

News & Media

Formal & Business

Human-verified examples from authoritative sources

Exact Expressions

7 human-written examples

Chronic exposure of swine industry workers to airborne barn dust results in significant predisposition to airway diseases and impairment of alveolar macrophage (AMϕ) function.

Veterinary Immunology and Immunopathology

However, it is a common opinion that ligament tears and secondary joint laxity lead to significant predisposition to articular cartilage degeneration secondary to altered knee forces.

Journal of Orthopaedics and Traumatology

Paracchini et al. [12] reported that haplogroup O-M122-derived lineages (O3 in their paper) were associated with a statistically significant predisposition to prostate cancer in their Japanese sample.

Plosone

There was no significant predisposition to these operative procedures between the two groups.

Diabetes Care

The DMA*0101 allele was observed to confer a significant predisposition to this autoimmune disease while the DMA*0102 allele protected significantly.

Disease Markers

Germ-line mutations of KMT2D are associated with Kabuki syndrome, an autosomal dominant disease characterized in part by immunological defects, but without a significant predisposition to lymphomas.

Blood Cancer Journal

Human-verified similar examples from authoritative sources

Similar Expressions

53 human-written examples

Increasing evidence suggests that there is a significant genetic predisposition to cerebrovascular disorders, and these genetic risk factors may account for some portion of the unexplained risk of stroke [ 1– 4].

BioMed Research International

While familial risk factors account for a significant rate of predisposition to schizophrenia, there is evidence of an important environmental contribution [ 17, 32].

BMC Psychiatry

The Predominance of Verbal and Imagery-based Thoughts VAS (Section 5.5.7) has been used with bipolar patients to demonstrate a significant predisposition towards imagery-based processing styles (Holmes et al., 2011).

Clinical Psychology Review

The observed AATF gene alterations lacked association with breast cancer risk and therefore mutations in this gene are likely not to play a significant role in hereditary predisposition to this malignancy.

BMC Cancer

We further adjusted for the interaction terms between the genetic risk score and the factors that previously showed a significant interaction with genetic predisposition to adiposity (sugar sweetened beverages, physical activity, and television watching), 6 7 and the results remained unchanged.

British Medical Journal

Expert writing Tips

Best practice

When using the phrase "significant predisposition to", ensure it's followed by a specific condition, behavior, or outcome. For example, "significant predisposition to anxiety" or "significant predisposition to certain diseases".

Common error

Avoid using "significant predisposition to" without a clear and specific outcome. Instead of saying "a significant predisposition", specify what the predisposition is towards to maintain clarity and relevance.

Linguistic Context

The phrase "significant predisposition to" functions as a descriptor indicating a notable tendency or susceptibility towards a specific condition or outcome. As Ludwig AI suggests, it highlights an increased likelihood rooted in various factors.

Expression frequency: Uncommon

Frequent in

Science

70%

News & Media

15%

Formal & Business

10%

Less common in

Encyclopedias

2%

Reference

2%

Wiki

1%

Ludwig's WRAP-UP

The phrase "significant predisposition to" is grammatically correct and denotes a notable tendency or susceptibility towards a specific condition or outcome. As highlighted by Ludwig AI, it effectively communicates an increased likelihood. Predominantly used in scientific and formal contexts, it's essential to follow it with a clear and specific outcome to avoid vagueness. Alternatives such as "increased susceptibility to" or "heightened vulnerability to" offer similar meanings. Remember to specify the condition to which there is a predisposition to ensure clarity in your writing.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

predisposed to developing

Adds "developing" to emphasize the process of acquiring a condition.

increased susceptibility to

Replaces "predisposition" with "susceptibility", focusing on vulnerability.

heightened vulnerability to

Emphasizes the increased weakness or openness to harm.

demonstrating a clear susceptibility towards

Emphasizes the evident vulnerability or openness to something.

greater inclination towards

Uses "inclination" to suggest a natural tendency.

showing a marked tendency for

Highlights the exhibited trend or pattern.

increased likelihood of

Focuses on the probability of something occurring.

tendency to develop

Highlights the potential for development of a condition or trait.

prone to

A simpler, more direct way of saying someone is likely to experience something.

at higher risk of

Focuses specifically on the elevated risk associated with a condition or event.

FAQs

What does "significant predisposition to" mean?

It indicates a notably increased likelihood or tendency to develop a particular condition, behavior, or outcome. It suggests a strong inclination influenced by factors like genetics or environment.

How can I use "significant predisposition to" in a sentence?

You can use it to describe someone's increased susceptibility. For example, "Individuals with a family history of heart disease often have a "significant predisposition to" developing the condition themselves".

What are some alternatives to "significant predisposition to"?

Alternatives include "increased susceptibility to", "heightened vulnerability to", or "greater inclination towards", depending on the context.

Is it better to say "predisposition for" or "predisposition to"?

"Predisposition to" is the more commonly accepted and grammatically standard form. While "predisposition for" might be used informally, "predisposition to" is preferred in formal and academic writing.