significant irritation

USAGE SUMMARY

The phrase "significant irritation" is correct and usable in written English.
It can be used to describe a level of annoyance or discomfort that is considerable or noteworthy. Example: "The constant noise from the construction site caused significant irritation among the residents."

✓ Grammatically correct

Science

Wiki

News & Media

Human-verified examples from authoritative sources

Exact Expressions

12 human-written examples

The results showed that the physicochemical characteristics and catechin level of the drug-loaded microemulsion did not show significant degradation after 3 months of storage at 25 °C.The catechin-loaded microemulsion did not cause significant irritation compared to the water-treated group.

Colloids and Surfaces B: Biointerfaces

They can, however, cause significant irritation of the skin.

Wikipedia

Its effects in humans start at concentrations lower than hydrogen cyanide's 50 ppm and are similar to those of chlorine: significant irritation of the eyes and respiratory system as well as liver and kidney damage occur above 25 ppm.

Wikipedia

For example, while benzyl benzoate is highly effective in vitro, it can cause significant irritation when used to treat people and needs to be diluted for use in children.

Plosone

This is particularly important for ammonia where elevated short-term exposures can result in significant irritation and health effects.

Environmental Health: A Global Access Science Source

The aim must be to use the highest concentration that can be tolerated without significant irritation of the skin.

Clinical interventions in aging

Human-verified similar examples from authoritative sources

Similar Expressions

48 human-written examples

In a controlled experiment where 20 healthy individuals were exposed to woodsmoke combustion with PM2.5 levels ranging from 165 to 303 μg/m and 205 to 662 μg/m for low and high exposure, respectively, significant mucosal irritation was detected, assessed using a standardized self-reported rating scale of irritation of the throat, nose, and eyes (Riddervold et al. 2011).

Environmental Health Perspectives

In people with existing respiratory disease this can cause significant airway irritation and breathing difficulties.

BBC

Elastomeric thread or chain requires frequent replacement and reactivation, whilst NiTi coil springs often cause significant tissue irritation and hyperplasia.

Progress in Orthodontics

These results suggest that lunar dust like that returned aboard Apollo 14 will not cause significant eye irritation once nominal operations commence on the lunar surface.

BMC Ophthalmology

Formaldehyde exposures to 0.7 ppm for 4 h and to 0.4 ppm for 4 h with peaks of 0.8 ppm for 15 min caused no significant sensory irritation of the measured conjunctiva and nasal parameters.

Archives of Toxicology

Expert writing Tips

Best practice

When describing the results of a clinical trial or experiment, quantify the level of "significant irritation" observed to provide more context. For example, indicate the percentage of participants reporting irritation or use a standardized irritation scale.

Common error

Avoid using "significant irritation" when the level of discomfort or annoyance is minor or negligible. Choose a more appropriate term to accurately reflect the situation.

Linguistic Context

The phrase "significant irritation" functions primarily as a noun phrase, where the adjective "significant" modifies the noun "irritation". It describes a degree or extent of the irritation. As Ludwig AI confirms, this phrase is correct and usable in written English.

Expression frequency: Uncommon

Frequent in

Science

70%

News & Media

15%

Wiki

15%

Less common in

Formal & Business

0%

Encyclopedias

0%

Reference

0%

Ludwig's WRAP-UP

In summary, "significant irritation" is a grammatically sound and usable phrase that describes a notable level of discomfort or annoyance. Ludwig AI confirms its correctness. While relatively uncommon, this expression finds its primary usage in scientific, news, and general contexts. When using this phrase, ensure that the level of irritation is indeed considerable and that the term aligns with the specific context. Alternatives such as "considerable discomfort" or "substantial annoyance" may be suitable depending on the situation. Remember to quantify the level when possible for accuracy.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

considerable discomfort

Emphasizes the physical or emotional unease caused, rather than the triggering factor.

substantial annoyance

Highlights the feeling of being bothered or disturbed.

marked inflammation

Focuses on the physical response of the body, specifically in cases of skin or tissue irritation.

noticeable aggravation

Suggests a worsening of a pre-existing condition or sensitivity.

pronounced sensitivity

Implies a heightened reaction to a stimulus.

severe vexation

Indicates a strong feeling of frustration or irritation.

intense discomfort

Focuses on the high level of pain/suffering caused.

major disturbance

Highlights the interruption or disruption caused by the irritating factor.

acute sensitivity

Emphasizes a sudden and intense reaction.

extreme bother

Focuses on the high level of distress caused.

FAQs

How can I use "significant irritation" in a sentence?

You can use "significant irritation" to describe a noticeable level of discomfort or annoyance caused by something. For example: "The new medication caused "significant irritation" to the patient's skin."

What are some alternatives to "significant irritation"?

Alternatives include "considerable discomfort", "substantial annoyance", or "marked inflammation", depending on the specific context.

What is the difference between "significant irritation" and "mild irritation"?

"Significant irritation" implies a more pronounced and bothersome reaction, whereas "mild irritation" suggests a less intense and more tolerable level of discomfort.

Is it better to use "significant irritation" or "severe irritation"?

"Severe irritation" indicates a higher degree of intensity compared to "significant irritation". The choice depends on accurately representing the level of discomfort experienced. Consider the scale of the impact to determine the appropriate wording.