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Exact(6)
Having chosen a feature set and HMM topology to model the events of interest, a significant effort is required to train a HMM system.
In particular, we identify the area of quantitative watershed hydrogeophysics as a frontier area, where significant effort is required to advance the estimation of hydrological properties and processes (and their uncertainties) over spatial scales relevant to the management of water resources and contaminants.
It is apparent that significant effort is required to fully understand how Chlamydia occupies its niche.
However, collaborative processes are time consuming and significant effort is required to communicate and achieve consensus [ 16].
This is a significant obstacle to their reusability, as significant effort is required to adapt them to modeling software other than the ones they were constructed with.
Given the enormous public health implications of overweight and obesity in the population, these findings suggest that significant effort is required to tackle unhealthy weight in children in all local authorities and that this should be a priority in areas with high levels of deprivation.
Similar(54)
"The full extent of any errors in the calculation and payment of royalties has been been quantified," the report said, adding that "significant effort" was required to resolve the status of another $281.4m in operating expenditure deductions and $21.1m in capital expenditure deductions.
Significant efforts are required to establish its theoretical foundation for a cost-effective method.
Significant efforts are required to overcome the HIV and TB epidemics, address persistent health inequalities, improve the quality of health care provision, and improve health outcomes (6).
Although minimum reporting standards related to metabolite identification were published in 2007, it is clear that significant efforts are required to ensure their continuous update and appropriate use by the metabolomics community.
However, to achieve this promise of WGS in research focused on crop improvement, significant efforts are required in functional genomics that include gene annotation, cloning, expression, and further functional analysis.
Related(20)
considerable effort is required
major effort is required
large effort is required
tremendous effort is required
substantial effort is required
significant effort is needed
significant effort is laid
significant bandwidth is required
significant improvement is required
significant risk is required
significant research is required
significant infrastructure is required
significant wisdom is required
significant response is required
significant validation is required
significant effort is directed
significant backoff is required
significant rearrangement is required
significant expertise is required
significant effort is devoted
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