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Exact(3)
This makes the method unattractive both technically and economically: a large effort is required for engineering NPs with the correct properties, the risks associated are clogging and pressure increase, and the method is expensive.
However, use of unlabeled compounds precludes measurement of the uptake and binding of compound metabolites and a large effort is required to obtain data for full pharmacokinetic analysis, because each animal can only provide information for a single time-point.
The systematic review approach is potentially more thorough, as it seeks to identify and utilise all existing evidence, but it is also more resource intensive [ 14] as large effort is required to identify relevant studies, liaise with study authors, and then obtain and clean IPD provided.
Similar(57)
HP will continue to focus on the energy issue, but a larger effort is required.
A significantly larger and sustained effort is required to transition the nation's massive energy system to a new, clean energy economy - a fact President Obama and the American public cannot afford to forget.
Given the large amount of data generated by CLIP-Seq, considerable computational effort is required to generate reliable quantitative information of protein-RNA interactions [ 35].
No attention effort is required.
A similar effort is required now.
"A national effort is required.
Effort is required to sustain them.
The windows were difficult to dislodge, since their ancient glazing putty was rock hard, and chisels and days of effort were required to release the larger windows.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com