Sentence examples for severely hindering from inspiring English sources

Together these data indicate that the manifestation of neurological symptoms influences the development/growth of several vital organs to different extents, severely hindering immune-competence in Rac1N/Rac3KO double-mutant mice.

One disadvantage of using these fluorescent dye labeled aptamers on their own is that they are rapidly photobleached, severely hindering their clinical usefulness [14].

But the support they received from this short-term program was quite limited, Gebai explains, severely hindering their ability to assist refugees.

The beachhead was now filled to capacity with troops, to the point that "B" Company of the Chaudières could not be deployed alongside "C" Company without severely hindering the advance of the QOR to their east.

Our findings suggest that perturbation of gp78 function occurs by three interrelated mechanisms: 1) polyglutamine expansion enhances mutant htt interaction with the cue domain of gp78, thereby severely hindering polyubiquitin binding to the cue domain; 2) mutant htt sterically blocks p97/VCP interaction with gp78; 3) accumulation of mutant htt causes aggregation of gp78.

This fits perfectly with the notion that many particularly C + G rich elements (including CpG islands) across the genome influence the efficiency of analysis of surrounding contiguous sequences by severely hindering DNA denaturation.

Large scale applications of microbial fuel cells (MFCs) have been severely hindered by several problems such as high internal resistance, low power output, expensive materials, and complicated configuration.

Alternatively, the distribution of pairwise distances between copies may provide quantitative results, but ancient transposition events (deep and bushy nodes in the tree) are counted several times, which severely hinders data interpretation.