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The neuronal restrictive expression of SP4 gene prevented our further effort to investigate the effects of the positive SNPs on the level of human SP4 gene expression.
Unfortunately, the neuronal restrictive expression of SP4 gene prevented our further effort to study the association between these positive SNPs/haplotypes and the level of human SP4 gene expression.
The remaining half was found in less than 3 libraries, indicating a more restrictive expression.
Murine models may therefore represent an imperfect model of CD28 function in humans, with its more restrictive expression patterns on naïve and central memory CD4+ and CD8+ cells.
Although ANXA1 expression seems quite unique among healthy human tissues, each tissue shows rather restrictive expression of ANXA1: e.g., highest in the liver, 6.5-fold compared with the calibrator tissue (bile duct).
Cancer-testis (CT) antigen (Ags) represent a family of proteins widely studied in the field of cancer immunotherapy because of their restrictive expression pattern and immunogenicity in cancer patients [ 1].
Similar(52)
The insufficient upregulation of HMGB1 in Atxn1-KI HMGB1 mice and the cerebellum-restrictive expression in AAV1-HMGB1-infected mice might be partially responsible.
To gain molecular insight to this restricted expression, we compared histone modifications and nucleosome occupancy in this intron between expression permissive and restrictive cell lines.
Thus, restrictive spatial expression patterns might be a common feature of mRNA-like ncRNAs.
We also found that SS-HCV patients with monoclonal gammopathy had a more restrictive monoclonal expression (overwhelmingly limited to either mIgMk or mIgG) compared with patients without HCV, who presented all types of monoclonal heavy and light chains.
We show that a conserved neuron-restrictive silencer element (NRSE) can function to restrict transgene expression to the nervous system.
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