Used and loved by millions
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
requires substitution
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "requires substitution" is correct and usable in written English.
It can be used in contexts where something needs to be replaced or exchanged for another item or value. Example: "The formula in this equation requires substitution to solve for the variable."
✓ Grammatically correct
Science
News & Media
Academia
Alternative expressions(1)
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
3 human-written examples
The main aims of this paper are (1) to demonstrate that the effective and efficient application of the GA concept to design problem solving requires substitution of the basic GAs natural evolution by genetic engineering (GE), (2) to propose and discuss the concept of a genetic engineering algorithm (GEA), and (3) to show how to apply the GEA to solve synthesis problems.
It is assumed that providing maize for the fermentation process requires substitution of feed, e.g. by import, and therefore increases the ecological pressure on field by 20%.
Block of SOCE apparently requires substitution with bulky, electron-drawing groups in C3.
Human-verified similar examples from authoritative sources
Similar Expressions
57 human-written examples
The Dane injured himself badly enough in the process to require substitution.
News & Media
Computer-aided aroma design (CAAD) is likely to become a hot issue as the REACH EC document targets many aroma compounds to require substitution.
L. 94 210 was executed by substituting "person leased" for "railroads leased" to reflect the probable intent of Congress, notwithstanding such section 607 s) requiring substitution of "person leased" for "railroad leased".
Academia
The United States Court of Appeals for the Ninth Circuit ruled that the district judge handling the case was required to examine the facts and decide "whether the interests of justice required substitution of counsel" when the inmate, Kenneth Clair, complained that his lawyer was not pursuing important evidence in his federal habeas corpus appeal.
News & Media
This study assessed individual SNP genotyping precision using the Ion PGM™, the forensic sensitivity of the multiplex using dilution series, degraded DNA plus simple mixtures, and the ancestry differentiation power of the final panel design, which required substitution of three original ancestry-informative SNPs with alternatives.
These units aim at receiving patients who need close monitoring, or present a risk of a potential organ failure without requiring substitution.
Science
Although various oligonucleotide backbone modifications have been invented for more efficient binding to complementary RNA [23, 24], these modifications require substitution of multiple nucleotides.
Science
A decision to ban or to phase out use of glyphosate will hurt both farmers and consumers by decreasing crop yields, increasing the costs of produce, and requiring substitution of herbicides about which less is known and which may pose a greater health risk.
News & Media
Expert writing Tips
Best practice
When writing technical documentation, clearly specify what element "requires substitution" and what the potential substitutes are. This avoids ambiguity and aids understanding.
Common error
Avoid using "requires substitution" without clearly stating what needs to be substituted. For example, instead of saying "This requires substitution", specify "This component requires substitution with a heat-resistant alternative".
Source & Trust
82%
Authority and reliability
4.1/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "requires substitution" functions as a verb phrase combined with a noun. The verb "requires" indicates a necessity or obligation, while "substitution" specifies the action needed: replacing something with something else. Ludwig AI confirms its use in various contexts.
Frequent in
Science
65%
News & Media
18%
Academia
17%
Less common in
Encyclopedias
0%
Wiki
0%
Formal & Business
0%
Ludwig's WRAP-UP
In summary, the phrase "requires substitution" is a grammatically correct way to express the necessity of replacing something with something else. Ludwig AI highlights its primary contexts in scientific, news, and academic fields. To ensure clarity, always specify what needs to be substituted. While alternatives like "necessitates replacement" or "calls for replacement" exist, the choice depends on the desired level of formality and specificity. By following best practices and avoiding common errors, writers can effectively use this phrase in their writing.
More alternative expressions(10)
Phrases that express similar concepts, ordered by semantic similarity:
necessitates replacement
Emphasizes the unavoidable need for a complete change.
calls for replacement
Suggests a strong need for a new component or element.
demands a substitute
Highlights a stringent requirement for a stand-in.
entails a replacement
Implies that substitution is a logical consequence.
mandates a substitute
Indicates that substitution is officially required.
needs to be replaced
A more direct way of saying something must be changed.
compels a substitution
Highlights a forced action of replacing something.
involves a swap
Indicates a simple exchange of one thing for another.
prescribes an alternative
Suggests a recommended replacement, often in a technical context.
suggests switching
A less formal way of proposing a change.
FAQs
How can I use "requires substitution" in a sentence?
You can use "requires substitution" to indicate that something needs to be replaced or exchanged, such as "The damaged part "requires substitution" with a new one."
What are some alternatives to "requires substitution"?
Alternatives include "necessitates replacement", "calls for replacement", or "demands a substitute", depending on the context.
Is it better to say "requires substitution" or "needs replacement"?
"Requires substitution" is more formal and specific, while "needs replacement" is more general. The best choice depends on the context and audience.
What does it mean when something "requires substitution" in a scientific context?
In a scientific context, "requires substitution" often indicates that a specific element, such as a chemical or a procedure, must be replaced with another to achieve the desired outcome or to correct a problem.
Editing plus AI, all in one place.
Stop switching between tools. Your AI writing partner for everything—polishing proposals, crafting emails, finding the right tone.
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
82%
Authority and reliability
4.1/5
Expert rating
Real-world application tested