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Exact(4)
The proposed approach aims to significantly reduce the time required for method optimization as well as the extent of experimentation.
The components drawn in green are used only to perform separations according to Method A, the parts required for Method B are shown in red, while black indicates the apparatus components used for both methods.
Figure 1g shows the skewed distribution of the GH dimension and that the underlying assumption of Normality of the distribution required for Method 1 may not be appropriate.
No preparation step was required for Method A, whereas deparaffinization was required for Methods B and C. For tissue deparaffinization, 200 µL xylene was added to whole, half, and quarter portions of one tissue section (2 mm circle of 4 µm thickness) and agitated for 5 minutes, then centrifuged at 12,000 rpm for 10 minutes.
Similar(55)
The detection level stated in this paper reflects the lowest reproducibly detected level in this study, as such it is not a fully validated limit of detection (LOD) as required for methods for legal purposes.
Unlike other CTC detection methods, further enrichment from white blood cells is not required for this method owing to the highly sensitive and specific detection system employed.
No smart decision is required for this method.
The price of equipment required for this method is also more affordable.
Meanwhile, 375 min is required for the method in [2, 4, 5].
Table 3 tabulates the processing time required for each method to process images with various sizes.
The main inputs required for this method is a digital elevation model (DEM), initial height and area of the mixture (pile height) and basal and internal friction values.
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