regulated cell death

USAGE SUMMARY

"regulated cell death" is correct and usable in written English. You can use it in contexts related to biology, medicine, or cellular processes. Example: "Apoptosis is a form of regulated cell death that plays a crucial role in development." Alternative expressions include "controlled cell death" and "programmed cell death."

✓ Grammatically correct

Science

Academia

News & Media

Human-verified examples from authoritative sources

Exact Expressions

58 human-written examples

Therefore, it is likely that the SPL5 regulated cell death and resistance responses post-transcriptionally.

Rice

These results suggest that the developmentally regulated cell death observed in some XB21 overexpressing plants is also regulated by additional, unidentified abiotic factors.

Rice

Recent advances in the genetic manipulation of regulated cell death and danger-associated molecular patterns and 'alarmins', such as HMGB1 and the IL-1 family, may hold the key to delineating the consequences of cell death in immunity to infection.

Current Opinion in Immunology

In plants and human, the phosphatase 2c negatively regulated cell death and oncogenicity, respectively [ 74, 75].

BMC Plant Biology

Apoptosis is a highly regulated cell death programme triggered by a diverse array of cellular stresses.

British Journal of Cancer

For example, Atg7 and Becn1 regulated cell death in mouse L929 cells treated with the pan-caspase inhibitor.

Autophagy

One hallmark of cancer cells is their ability to evade physiologic signals causing regulated cell death (RCD).

Cell Communication and Signaling

IRE1 α re-introduction rescued calcein-AM signal loss in IRE1 α-KD cells (Supplementary Figure S2b), indicating that altered IRE1 α levels regulated cell death.

Cell Death and Disease

On the other hand, necroptosis or programmed necrosis is a form of highly regulated cell death that morphologically resembles necrosis [24].

Clinica Chimica Acta

Human-verified similar examples from authoritative sources

Similar Expressions

2 human-written examples

In the shift from transition phase to white adipose phase, we did observe an up-regulation of genes related to cell death, but nearly half of the up-regulated cell death associated genes are negative regulators of cell death (Table  2).

BMC Genomics

We determined the role of p53 and WOX1 in C1q-regulated cell death.

Plosone

Expert writing Tips

Best practice

In scientific papers, specify the type of RCD (e.g., apoptosis, ferroptosis, or necroptosis) after the first general mention to provide better technical clarity.

Common error

Do not use "regulated cell death" when referring to death caused by extreme external factors like heat or mechanical stress, which is more accurately called accidental cell death (ACD). RCD implies a functional machinery within the cell is actively executing the process.

Linguistic Context

In a sentence, "regulated cell death" functions as a complex noun phrase. It typically acts as the subject or the direct object of verbs related to biological signaling. According to Ludwig, it is frequently used to categorize physiological responses that are distinct from uncontrolled necrosis.

Expression frequency: Very common

Frequent in

Science

85%

Academia

10%

News & Media

5%

Less common in

Formal & Business

2%

Encyclopedias

1%

Social Media

1%

Ludwig's WRAP-UP

The term "regulated cell death" is a cornerstone of modern biology, appearing in over 50 authoritative examples provided by Ludwig AI. It is essential for writers in medical and scientific fields to use this phrase when referring to cellular termination that is under genetic or biochemical control. Unlike accidental death, "regulated cell death" implies a functional mechanism that can be targeted by therapy or observed during natural development. Using this phrase correctly demonstrates a high level of scientific literacy and precision.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

programmed cell death

implies a predefined developmental or genetic schedule

mediated cell death

highlights the involvement of specific signaling agents or pathways

apoptotic cell death

specifies the non-inflammatory morphological type of death

controlled cell death

uses more general vocabulary for the same biological concept

necroptotic cell death

refers to a specific regulated form of necrosis

genetically encoded cell death

focuses on the molecular instruction set behind the process

physiological cell death

emphasizes the natural context within a healthy organism

cellular suicide

provides a more figurative and accessible description

active cell death

contrasts the process with passive or accidental death

autophagic cell death

identifies death resulting from excessive self-digestion

FAQs

What is the difference between "regulated cell death" and apoptosis?

While apoptosis is a form of "regulated cell death", the latter is a broader term that also includes other controlled mechanisms like "necroptosis", "ferroptosis", and "pyroptosis".

Can I use "programmed cell death" as a synonym?

Yes, but "programmed cell death" often refers specifically to death during development, whereas "regulated cell death" covers responses to stress or injury as well.

How do I use "regulated cell death" in a sentence?

A common way to use it is: "The drug was found to induce "regulated cell death" in resistant cancer cells through a caspase-independent pathway."

Is "regulated cell death" formal enough for a thesis?

Absolutely. It is the preferred technical terminology in modern biomedical research as highlighted in various scientific journals found on Ludwig AI.