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The ARLD is composed of fourteen helices (α1 to α14, Fig. S1) that may provide a platform for interactions with other partners.
It also provides a platform for interactions with the dissociable cyclin-dependent kinase 8 (Cdk8) module, which could repress activated transcription.
Both biochemical and genetic evidence places the CTD in a central position in the 'mRNA factory,' where it functions as a platform for interactions with processing factors and other transcription-related proteins [ 19, 20].
These motifs are important features of diverse protein-protein interactions [ 4], providing an unbending platform for interactions of proteins with other cellular components and controlling therefore several vital functions of the cell, such as signaling cascades, cellular transport and apoptosis [ 29- 31].
The phosphorylation event serves as an important cue for the stable retention of DNA damage repair and DDR mediator proteins in close proximity to DSBs, resulting in the formation of microscopically discernible foci that function as a platform for interactions between multi-component signal transduction complexes, facilitating the activation of the cell cycle checkpoint [ 58- 60].
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The BASD Business Day, June 19 in Rio, will be the headline business event at Rio+20, and will provide a high-profile platform for interaction between business leaders and policy-makers.
The slang of social networks will also move from the schoolyard to the boardroom: it is only a matter of time before middle-aged managers talk about "poking" when planning marketing campaigns.Anything 2.0 Web 2.0 is a dull piece of jargon to describe the internet becoming a platform for interaction and collaboration.
Furthermore, there is no common platform for interaction between policy makers, scientists and other societal representatives.
Not only are those mechanisms essential for the survival of the cells, but they also provide an incredible platform for interaction between cells of all domains.
The C-terminal helicase domain is not catalytically active, but serves as a platform for interaction with many spliceosomal components [ 26, 37].
On the other hand, the sequence content of the 3′ UTR of a single transcript offers a platform for interaction with a number of miRNAs.
Related(15)
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