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Understanding the mechanistic basis for interactions of these novel targeted agents with DNA-interactive drugs will inform design of optimal combinations for future studies and is critical to maximize benefit in the clinic.
This system provides the basis for interactions between stimulus reward associative processing in the amygdala and the primary site mediating the reinforcing effects of addictive drugs, the ventral striatum, thereby underlying both pavlovian and instrumental appetitive behaviours – much as Mogenson et al. (1984) had predicted when describing this system as a 'limbic-motor interface' (Fig. 2).
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During viewing, interactions decreased in quantity and quality across groups; however, parents used video content as a basis for interaction.
The molecular basis for interaction of Gβγ with effectors was characterized by mutational analysis of Gβ residues that make contact with Gα-GDP.
Collectively, close understanding on the structural basis for interaction is given which might establish a basis for design of suramin analogues targeting thrombin.
The co-crystal structure describes a structural basis for interaction and provides a firm foundation for structure-assisted design of lead compounds with appropriate molecular properties for future drug development.
The authors may elaborate on this part, particularly the basis for RH-RH' interaction.
Considering complementarity as the basis for interaction with regulatory elements, we could also describe this observation as an increase in the variance of sequence interactivity.
A robot's analysis of natural language and non-verbal expressions can recognise different emotional states as a basis for interaction (e.g. Saint-Aimé et al. 2010).
Previous data about different maternal exposures and smoking during pregnancy used herein as a basis for interaction analysis are described elsewhere [ 30, 32].
With the decline in timber, cattle and other commodity markets, the basis for interaction and reciprocity among rural landowners in eastern Oregon has become scarce.
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