Sentence examples for persistence of expression from inspiring English sources

Increased levels of red cell fetal hemogloblin, whether due to hereditary persistence of expression or from induction with hydroxyurea therapy, effectively ameliorate sickle cell disease (SCD).

We also demonstrate other interesting features of the retinal transcriptome, for example, that the retina appears to employ a very specific and restricted set of synaptic vesicle genes, and also that there is persistence of expression of a majority of "neurodevelopmental" genes into adulthood.

The relative importance of this mechanism compared with more well-established modes of expression instability [5], such as the permanent loss or rearrangement of transgene copies, will depend on the amplitude and persistence of expression fluctuations, which are expected to be system-dependent.

Persistence of expression in the mac1 mutant of transcripts that are normally downregulated to very low levels or are completely missing substantiates the idea that transient suppression of many transcript types is an important developmental feature of the 0.4 mm stage during which newly established cell types begin to differentiate and proliferate anticlinally to build a larger anther.

Overall, we assessed the levels of persistence of adenovirus expression in infected cells, as the down-regulation of HES1 expression due to miR199b carrying the adenovirus expression, thus following tumor growth over time by BLI see Figure 4G H, and antibodies staining Figure S4L M (Hes1, Ki67, Gabra6, Nestin, Math-3, see details in Text S1 information).

Objective To determine whether use of cannabis in adolescence increases the risk for psychotic outcomes by affecting the incidence and persistence of subclinical expression of psychosis in the general population (that is, expression of psychosis below the level required for a clinical diagnosis).

We therefore speculate that loss of OCT4 expression prior to GC migration to the basal membrane is important, and that persistence of OCT4 expression in some GC, combined with their abnormal location in the basal niche may, in the human, predispose such GC to becoming CIS.

Persistence of nkx6.1 expression in the zebrafish ducts is also associated with persistence of another pancreatic progenitor marker, pdx1, whose expression is also restricted to beta cells in mammals.

Importantly, these experiments suggest an explanation for the persistence of Nkx2.2 expression in the p3 domain in vivo, despite the level of Gli activity and Gli1 and Gli2 expression in these cells decreasing with developmental age.

Although it is not possible to directly fate-map the neural crest and parietal mesoderm in rat embryos, the loss of Hmx1 expression in the dumbo rat appears to be largely confined to the neural crest compartment, with persistence of Hmx1 expression in the mesoderm-derived CM (compare Fig. 5, L5 with Fig. 6D and Fig. 5, L7 with Fig. 6E).

HC-AdVs were shown to result in long-term persistence of transgene expression and phenotypic correction in small and large animal models with negligible toxicity.