Glucose homeostasis is affected by the peripheral glucose uptake [33].
The hepatic glycogen reservoir limits the peripheral glucose uptake for prolonged exercise.
This may be a consequence of altered glycogen metabolism and inhibition of peripheral glucose uptake through Glut4 [26].
In this work, the problem of controlling the glucose concentration in Type 1 Diabetes Mellitus (T1DM) patients is addressed, with discrete-delayed measurements of peripheral glucose concentration.
The immediate consequences of exercise are incorporated in this research: redistribution of blood flows, increments in peripheral glucose and insulin uptakes, and increment in hepatic glucose production.
ITT (i.e. as a measure of insulin-dependent peripheral glucose uptake).
Peripheral glucose uptake was determined using Mari's non steady-state equationon steady-state
Glucose homeostasis is maintained by a balance between hepatic glucose production and peripheral glucose utilization.
Lack of CgB might affect peripheral glucose uptake, as was recently shown for CgA [29].
As central leptin signaling has been implicated in the control of peripheral glucose homeostasis, here we examined the ability of central intracerebroventricular leptin administration to affect energy balance and peripheral glucose homeostasis in non-obese diabetic male MKR mice.
The relationship between peripheral glucose and insulin levels is an important indicator of the overall insulin sensitivity of the animal.
