Sentence examples for pax expression from inspiring English sources

The PAX expression levels are decreased but more variable than the PBMC expression levels (ρ = 0.85).

For initially multimodal expression domains, we observed more complex expression pattern, e.g., single spots of En or Pax expression.

Furthermore, both steady states show a restriction of the En and Pax expression to the MHB region, which can also be observed in vivo[ 8].

These findings are consistent with previous reports that demonstrate PAX expression enhances cell growth and survival [ 15, 42], and upregulated BCL2 is found in gliomagenesis [ 21, 31].

These arise as En or Pax locally exceed the threshold of their mutual activation, yielding isolated point regions with maximal En or Pax expression, respectively.

In gliomas, the chromosome 2q13 locus, where the PAX8 gene is located, is not a glioma susceptibility locus (OMIM #137800), but other mechanisms for the increased PAX expression in cancer have been described.

For the studies on the effects of constitutive Pax construct expression on differentiation, myogenic cells were left to reach confluency, at which point they began to spontaneously differentiate and fuse into myotubes, and were analysed five days post-infection.

Additionally, levels of PAX gene expression may reflect the cellular origin and stage of myogenic differentiation associated with the tumour.

Aberrant PAX gene expression is present in multiple cancer types, including cancers of the lymphoid tissue, thyroid, kidney, breast, and endometrium [ 7- 10].

In most cases, PAX gene expression attenuates when development is complete, but in a few tissues, it persists into adult life.

Paired box-containing proteins also possess many tumour-promoting functions, such as the promotion of cell survival and anti-apoptotic properties, because a reduction in PAX gene expression induces apoptosis in normal and tumour cells [ 11- 15].