Sentence examples for pathways to kill from inspiring English sources

Pioneers in Precision Medicine Interventional oncology is an image-guided, minimally invasive surgery done by radiologists that uses imaging scans as maps to identify the location of tumors and blood vessels as pathways to kill tumors or shrink and prepare them for removal.

Therefore, cotargeting HDACs and mutant BRAF can bypass canonical cell death pathways to kill BRAFV600E melanoma cells.

Regardless, the ability to bypass canonical cell death pathways to kill melanoma cells by combinations of HDAC and BRAF inhibitors may be of therapeutic advantage.

These findings also indicate that cytotoxic cells from invertebrates and jawless vertebrates must use alternative proteins or pathways to kill their target cells.

As shown previously, Listeriaat exhibits several pathways to kill tumor cells; that is, Listeriaat infects tumor cells in vivo and in vitro, and kills tumor cells directly through high levels of reactive oxygen species (ROS) 37.

In this study, the authors reported that combination of an oncolytic virus and chemotherapeutic agent could trigger specific DNA damage response pathways to kill cancer cells, including cancer stem cells.

Granzyme B (GrB), a component of the cytotoxic cell granule secretion pathway, is designed to kill infected and transformed cells after intracellular delivery by the pore forming protein, perforin.

Cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells use the secretory pathway of perforin/granzymes to kill their target cells.

We suggest that these patients, who would otherwise be stratified into a relatively low-risk group, should actually be considered as high-risk patients who would benefit from additional monitoring and therapy, possibly including the use of drugs to inhibit the PI3K pathway and/or strategies to kill p53 deficient tumour cells (Lane et al, 2010).

During acute inflammation, M1 macrophages become activated through a classical pathway and are able to kill and phagocytose tumour cells.

Though heme biosynthesis is not an essential pathway for blood-stage parasites (Ke 2014, Nagaraj 2013), our manuscript shows that this pathway is nonetheless targetable because stimulation of pathway activity can be exploited to kill parasites.