Increasing evidence has implicated PKC isoforms in nuclear functions, suggesting that they could represent a pathway to communicate to the nucleus signals generated at the plasma membrane [ 36].
This may be due to enhanced lysosomal and autolysosomal degradation occurring with proteasomal inhibition, as the different proteolytic pathways seem to communicate with each other.
This signaling pathway serves to communicate mitochondrial dysfunction to the nucleus to induce an appropriate transcriptional response.
For organs and tissues to develop in an embryo, signalling pathways help cells to communicate with each other.
Another distinctive mark of architecture among the artforms is its nontraditional status as a narrative medium: the design of circulatory pathways allows architectural objects to communicate a sequence of events through the movement of visitors or inhabitants.
In particular, the movement of calcium ions through the cell membrane has a central role in many of the signalling pathways that cells use to communicate with other cells.
Certain microorganisms have developed unique metabolic pathways, ecological adaptability, defenses, ability to communicate, and degradation and predation functions.
To reconstruct such models, SDREM starts with the upstream proteins that detect the invading pathogen and determines signaling pathways that allow such proteins to communicate with downstream TFs.
Late endosomes are arguably the most complex station of the endocytic pathway due to their ability to communicate with other organelles, i.e. inter organellar trafficking (with Golgi, lysosomes, ER), but also due to the communication between the intralumenal vesicles and the limiting membrane, i.e. intra organellar trafficking [5].
Intercellular signaling enables cell masses to communicate through endocrine pathways at a distance or by direct contact over shorter dimensions.
