over twofold

USAGE SUMMARY

The phrase "over twofold" is correct and usable in written English.
It can be used to indicate that something has increased by more than two times or has a ratio greater than two. Example: "The company's profits have increased over twofold since last year."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

60 human-written examples

Using gentamicin as the model drug, the MBGs scaffold can load over twofold higher amount of drug than the BGs scaffold.

Microporous and Mesoporous Materials

Fifty-five and 66% of those, respectively, also showed an over twofold difference in their expression levels.

BMC Cancer

Indeed, CD analysis revealed that incorporating a single proline into the TM of APP was sufficient to decrease TM helix stability by over twofold.

eLife

Additional filtration of the genes to include only those exhibiting an over twofold difference narrowed the list to 865 features (773 genes; Additional file 1, data sheet C).

BMC Cancer

Interestingly, these analyses revealed the presence of an over twofold significantly increased risk for hypertension incidence in women compared with men among those in the lowest HbA1c tertile (hazard ratio 2.24 [95% CI 1.17 4.27]).

Diabetes Care

Control neutrophils and normal-density SLE neutrophils had similar levels of copy number variations, while the autologous SLE LDGs had an over twofold greater number of copy number alterations per genome.

Arthritis Research and Therapy

To rule out that the vast decrease in invading U87-2M1 cells was attributed to apoptotic cell death after miR-10b inhibition, we transfected miR-10b mimics into U87-2M1 cells and observed an over twofold increase in invaded cells.

Cell Death and Disease

This is the first study to report an association between decreased odds for lymph node involvement and CYP2C8*4 and an over twofold increased odds for lymph node involvement among CYP2C8/9 *3/*1/*2/*1 carriers with invasive tumour sizes over 20 mm.

British Journal of Cancer

The study by Green and colleagues, which was based on an earlier version of CPRD with larger proportions of missing values and more exposure to etidronate than alendronate (57 v 37 exposed cases), reported an association with duration of treatment, with an over twofold increase in people who had been taking these drugs for more than three years (33 such cases).

British Medical Journal

The red panel indicates that the transcription level of gene increased over twofold; the green panel indicates the transcription level of gene decreased over twofold.

AMB Express

The red panel indicates the transcription level of gene increased over twofold; the green panel indicates the transcription level of gene decreased over twofold.

AMB Express

Expert writing Tips

Best practice

When using "over twofold", ensure the context clearly indicates what is being doubled or increased. Be specific to avoid ambiguity.

Common error

Avoid assuming "over twofold" always refers to a 100% increase from an initial value of 1. Clarify the reference point when comparisons are made from different baselines.

Linguistic Context

Over twofold functions as a quantitative adjective phrase modifying a noun, indicating a magnitude greater than two times a reference value. Ludwig AI shows its usage across scientific literature quantifying increases, differences, or risks.

Expression frequency: Very common

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Encyclopedias

0%

Ludwig's WRAP-UP

In summary, the phrase "over twofold" is a grammatically sound and frequently used expression to indicate that a quantity has increased to more than twice its original value. Ludwig AI confirms its prevalence in scientific and technical literature where precise quantifications are essential. While simpler alternatives like "more than double" exist for general use, "over twofold" maintains a level of formality and precision suited for academic and professional contexts. When using this phrase, clarity regarding the baseline and comparative elements is key to avoid misinterpretation.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

more than double

This alternative is simpler and more commonly used in general contexts.

more than doubling

This alternative focuses on the action of doubling and surpassing it.

greater than twofold

This alternative is more formal and emphasizes the excess over the doubling point.

beyond twofold

This alternative succinctly states that the amount is greater than double.

more than twice as much

This alternative is more explicit about the multiplication factor involved.

exceeding a twofold increase

This alternative is more descriptive and highlights the act of surpassing a doubling.

in excess of twofold

This alternative is a more formal phrasing emphasizing the amount exceeding the double.

over 200 percent

This alternative expresses the increase as a percentage.

at least twice as great

This alternative emphasizes the comparative magnitude of the increase.

in excess of 2x

This alternative is shorter and more technical.

FAQs

How can I use "over twofold" in a sentence?

Use "over twofold" to indicate that something has increased by more than two times its original value. For example, "The company's profits increased "over twofold" after implementing the new marketing strategy".

What's a simple way to say "over twofold"?

A simpler alternative to "over twofold" is "more than double". This is suitable for general contexts.

Is there a difference between "over twofold" and "twice as much"?

"Twice as much" means exactly double. "Over twofold" means more than double. For example, an increase from 10 to 25 is "over twofold", but it's not exactly twice as much.

When is it appropriate to use the phrase "over twofold"?

The phrase "over twofold" is appropriate in scientific, technical, and formal contexts where precise quantitative descriptions are necessary. In more casual writing, "more than double" might be preferred.