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In order to explore further the possibility that an RSS could orchestrate the sequence of VDJ recombination events, we used the transgenic VβDβJβECμ (hereafter TCRβwt) minilocus system.
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Apart from being a substrate of linear ubiquitination, NEMO was shown to bind linear linkages with 100-fold higher affinity than K63-linkages through its UBAN domain 41, 136, 137, suggesting that LUBAC, once recruited, orchestrates the sequence of events by enabling recruitment of NEMO via linear linkages on TNF RSC I components, like RIP1 and possibly others.
The morphologic changes that occur during fruiting body formation are accompanied by drastic changes in gene expression that are thought to orchestrate the spatiotemporal sequence of events that finally lead to the differentiation and dispersal of ascospores.
These appear to orchestrate a sequence of signalling events resulting in the progressive development of FD.
For example, BioVLab infrastructure [ 28, 36] built on the cloud is developed for genome analysis by utilizing the virtual collaborative lab, a suite of tools that allow scientists to orchestrate a sequence of data analysis tasks using remote computing resources and data storage facilities on demand from local devices.
For example, Bass's titles for Otto Preminger's 1959 film Anatomy of a Murder reduce a prone figure to disjointed parts, which move onto the screen in carefully orchestrated sequences that conclude with their positioning to form the figure; the lettering of the film's title appears as part of the sequence.
The sequence makes sense.
Her son, Dr. McDaniel, decided he would orchestrate the use of the most advanced techniques of gene sequencing and analysis to take on her cancer.
Seeds et al. used these sophisticated techniques, computer modeling, and behavioral observations to uncover how the brains of fruit flies orchestrate a grooming sequence.
Did the Cuban government orchestrate the incident?
Prosecutors contend that Mr. Bergrin helped orchestrate the killing.
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