Sentence examples for mutations with which from inspiring English sources

We can then measure the relative mixing ability of two mutations by holding constant the identity of other mutations with which the two of interest are mixed.

Six points are plotted above each pair of focal mutations, corresponding to the six different tester mutations with which each one was combined.

In this context, we can examine related sets of these single-double equations to ask whether one mutation is a better mixer than another in the context of the sample of mutations with which they were each tested.

While we analyzed the DNA sequence of the transduced gene in hChonJb 7, we detected additional mutations with which the wild-type threonine at position 84 and arginine residue at position 255 of the TGF-β1 precursor had changed into alanine and tryptophan respectively (A84/W255) in addition to the intended mutation of Cysteine 223 and 225 into Serine (S223/255).

Although our recommendations are pertinent to classical CF risk rather than the milder phenotypes discussed, there are some mutations that may be associated with mild or severe forms of CF depending on the mutations with which they are paired, thereby complicating the process of selecting mutation panels.

We show that the S116R mutation in human FGF-1 is accommodated with no perturbation of biophysical or structural properties, and is therefore an attractive mutation with which to elucidate the functional role of phosphorylation.

Our findings indicate that the effect of WT SOD1 on the toxicity of mutant SOD1 is influenced by both the nature of the fALS mutation with which it is co-expressed and the level of WT SOD1 expression.

The most likely source of the five exchanged fragments of NDsq0178 might come from NDsq0168 (sharing several highly specific mutations with NDsq0178), which was itself involved in sample mix-up.

While six of the cancers also carried a mutation in MLH1, with which MBD4 interacts, five of the tumours did not carry MLH1 mutations and in three the MLH1/MSH2 status was not known (Riccio et al., 1999).

These mutations are the pediatric counterpart of the recurrent IDH mutations [ 54, 78], with which they are also mutually exclusive.

For example, the order with which mutations arise in independent microcosms can potentially affect the fixation of subsequent mutations [50].