Sentence examples for mutations we report from inspiring English sources

Five of the mutations we report, four in KRAS and one in BRAF, have not previously been described in CRC.

These experiments show that the SCC4 mutations we report specifically impact cohesin recruitment to centromeres and the surrounding regions.

H3.3K36 methylation can be thus disrupted by H3.3 G34R/V mutation, IDH mutations and the SETD2 mutations we report herein (Fig.  2a, b).

Using ife-3 gene mutations, we report here additional novel roles for IFE-3 in postembryonic development, particularly in promoting the transition of the hermaphrodite germline from a spermatogenic to an oogenic tissue.

In the present study of murine models of Nde1 mutations, we report that Nde1 is indispensible for the successful completion of S phase, specifically during the early neuronal fate restrictive differentiation of multipotent neural progenitors.

The mis-sense mutations we report here most often affected hydrophobic amino acids, changing them to charged or polar amino acids, and five of the nine involve highly conserved residues.

Thus, the mutations we reported were done so with a high degree of confidence and we can clearly state that Carcinogenesis demonstrated a high degree of caution prior to acceptance of our results.

Further prospective or functional studies will be necessary to evaluate the predictive value of the remaining mutations, including the novel KRAS and BRAF mutations we here report.

To reduce potential false-positive calls of mtDNA somatic mutations, we only report variants called with an allele fraction of >3%.

However, this does not appear to be the case for the mutations that we report here because they actually slow the growth of tumor cells in vitro in normoxia where there is excess glucose and oxygen in the media [37].

To characterize the role of wild-type Ank and its mutants in the regulation of PPi transport in vitro, we stably transduced ATDC5 cells with wild-type Ank and three missense mutations we have reported in families with familial chondrocalcinosis.