Sentence examples for mutations we find from inspiring English sources

Reinforcing the notion that MELs are highly favoured targets for mutations, we find these areas are frequency mutated on both alleles: 48% of AID* genomes and 56% of sA3G* genomes have mutations within MELs occurring on both chromosome alleles, compared to just 2 3% predicted for random fragments of equivalent size and mutation loads.

So we need to find a way to spot cancer early, while also being certain that mutations we find are really on the path to becoming a potentially lethal tumor.

Combining the data from all ten output files (1 million total mutations), we find that just under 75% of the base changes were non-synonymous (causing a vector substitution).

In the limit β → 0, i.e., in the absence of phenotypic mutations, we find with Eqs.

In addition, focusing on somatic mutations, we find no differences between different tumor foci.

By examining antigenic mutations, we find a corresponding effect in simulated evolutionary trajectories (Table 1).

"Most of the mutations we found we can see in the field, and we are even seeing them in combination," he said.

In cardiomyopathy arising from sarcoglycan mutations, we found that endothelial nitric oxide synthase (eNOS) was significantly increased in focally damaged cardiac myocytes.

We applied this framework to de novo mutations collected from 1,078 ASD family trios, and, whereas we affirmed a significant role for loss-of-function mutations, we found no excess of de novo loss-of-function mutations in cases with IQ above 100, suggesting that the role of de novo mutations in ASDs might reside in fundamental neurodevelopmental processes.

Most of the somatic mutations we found have been reported, including mutations in EGFR, KRAS, BRAF, and PIK3CA [11] [17][11] [17].

Among 35 detected mutations we found 30 transitions, 3 transversions, 2 deletions (frameshift), 3 nonsense (stop), 26 missense and only 4 were synonymous.