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Justyna Jupowicz-Kozak

CEO of Professional Science Editing for Scientists @ prosciediting.com

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mutations to drive

Grammar usage guide and real-world examples

USAGE SUMMARY

The phrase "mutations to drive" is not correct and lacks clarity in written English.
It may be intended to convey the idea of using mutations to influence or propel a process, but it requires additional context to be fully understood. Example: "Scientists are exploring mutations to drive the evolution of more resilient plant species."

⚠ May contain grammatical issues

Science

Human-verified examples from authoritative sources

Exact Expressions

13 human-written examples

We therefore speculate that their presence may create a pro-oncogenic tissue environment that synergizes with oncogenic mutations to drive the rise in cancer incidence with age.

The genetic screens that led to the discovery of Hippo pathway factors in Drosophila relied on single recessive mutations to drive overgrowth phenotypes (reviewed by Hariharan and Bilder [43]).

First, genes called oncogenes can be activated by mutations to drive unscheduled cell division.

Science

eLife

These results indicate that activated Fgfr3 cooperates with other mutations to drive tumorigenesis in a tissue-dependent manner.

It is thus critical to identify these other signalling pathways that cooperate with these presumably initiating mutations to drive cancer.

The potential for germline p53 mutations to drive transactivation at selected miR-associated REs was also examined.

Science

BMC Cancer
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Human-verified similar examples from authoritative sources

Similar Expressions

47 human-written examples

Plasmids were constructed in which exon 3 of TGFBR2 and exon 10 of ACVR2 were cloned +1 bp out of frame, immediately after the translation initiation codon of an enhanced GFP (EGFP) gene, allowing a −1 bp frameshift mutation to drive EGFP expression.

Science

Plosone

Down-regulation of LKB1 may therefore serve as an alternative to p53 mutation to drive pancreatic cancer in vivo.

Taken together, these data suggest that K-Ras and β-catenin activating mutations do not cooperate with Fgfr3 mutation to drive UCC or to enhance signaling.

In addition, we have also shown that the β-catenin mutation can cooperate with H-Ras mutation to drive superficial bladder cancer (Ahmad et al., 2011b).

Moreover, identifying the cooperating molecular events that occur alongside FGFR3 mutation to drive UCC will aid the development of genetic models of UCC to test combinatorial therapies.

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Expert writing Tips

Best practice

Consider using more grammatically standard alternatives such as "mutations that lead to" or "mutations causing" for clearer and more effective communication. Precision in scientific writing is crucial for avoiding ambiguity.

Common error

Avoid using overly concise phrasing like "mutations to drive" which may lack clarity. Always prioritize grammatical accuracy and readability over brevity, especially in formal or scientific writing, to ensure your message is understood as intended.

Antonio Rotolo, PhD - Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Antonio Rotolo, PhD

Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Source & Trust

78%

Authority and reliability

3.3/5

Expert rating

Real-world application tested

Linguistic Context

The phrase "mutations to drive" functions as a purpose connector, attempting to link mutations with their intended effect. Ludwig AI notes that this phrasing is not grammatically correct and lacks clarity, suggesting a need for more precise language.

Expression frequency: Uncommon

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Social Media

0%

Ludwig's WRAP-UP

In summary, the phrase "mutations to drive" aims to express the causative role of mutations in influencing or propelling a process, particularly in scientific contexts. However, Ludwig AI identifies the phrase as grammatically incorrect and lacking clarity. While examples exist, especially within scientific literature, it's advisable to use more grammatically standard alternatives such as "mutations that lead to" or "mutations causing" to ensure precision and avoid ambiguity. Prioritizing accurate and clear communication will enhance the effectiveness of scientific and formal writing.

FAQs

What are some alternatives to "mutations to drive"?

You can use alternatives like "mutations that lead to", "mutations that cause", or "mutations responsible for" depending on the context.

Is "mutations to drive" grammatically correct?

No, according to Ludwig AI, the phrase "mutations to drive" is considered grammatically incorrect and lacks clarity in written English.

How can I use the phrase "mutations to drive" in a sentence?

While not grammatically ideal, you might see it in informal contexts. However, it's best to use more precise language such as "mutations that contribute to" or "mutations that promote" for clarity.

What is the difference between "mutations to drive" and "mutations that lead to"?

The phrase "mutations that lead to" is a grammatically correct and clearer way of expressing that mutations cause or result in a particular outcome, whereas "mutations to drive" is considered grammatically incorrect.

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Source & Trust

78%

Authority and reliability

3.3/5

Expert rating

Real-world application tested

Most frequent sentences: