Sentence examples for mutations so the from inspiring English sources

Of the 14 RCML patients, only one BC patients carried ABL kinase domain mutations, so the different metabolic phenotypes of RCML and SCML are not necessarily dependent on ABL domain mutations.

TFs have evolved by accumulating mutations, so the complexity in gene regulation patterns has increased.

Yet, in the early stages of the development of the culture there have not been enough generations to accumulate mutations, so the cells are genetically identical, nor is there any possibility of different environments in the constantly stirred culture.

In agreement with the hypothesis that reversion of mutations is driven by gain of fitness, Li et al. observed that reverting mutations preferentially arose within highly conserved residues and suggested that the severity of fitness loss associated with CTL escape mutations, so the strength of back selection, determines the kinetics by which escape mutations and reversions occur [38].

In both RIDL and SIT, some or all of the progeny of released individuals die as a consequence of inheriting one or more dominant lethal mutations, so the population tends to decline.

The iHS is designed to identify selective sweeps on new mutations, so the ancestral allele at rs748001 may be in LD with a derived allele that is experiencing a selective sweep.

The patches were chosen to make mutations so that the GRAVY values can approach closer to that of GGIVLTG patch [ 15] (Table 1).

Similarly, phosphorylation site peptides were matched to the wild-type variants of all mutations, so that the distance between each mutation and its closest phosphorylation sites could be determined.

There were no signs of recombination In the statistical parsimony (SP) analysis of 16S variation, haplotypes separated by up to eight mutational steps had a greater than 95% probability of being connected in a parsimonious fashion (i.e., no over imposed mutations), so that the criterion of parsimony could be assumed for all mutational connections in the network.

Thus, if adaptation is mutation limited, rates of adaptation are expected to be higher in species with larger N e, and given the higher efficacy of selection against mildly deleterious mutations, so is the proportion of divergence attributable to positive selection relative to mildly deleterious or neutral mutations.

On the scale of DNA, finding the mutations so far away from the gene was much like looking for one's car in a parking lot, and eventually finding it in a vacant field in another town.