Sentence examples for mutations results from from inspiring English sources

Moreover, in absence of any convincing data on the prognostic role of EGFR FISH or EGFR mutations, results from large phase III trials suggest that patients with clinical or biological predictors for TKI sensitivity survive longer when exposed to standard chemotherapy, a relevant aspect that should be considered in designing clinical trials.

We also discuss the possibility that the complementation of certain dpolv mutations results from trans-splicing.

DCM secondary to the Tnnt2 K210Δ mutation, and likely other sarcomeric protein mutations, results from abnormal function of a mutant protein and is associated with myocyte Ca2+ desensitization in vivo.

The premise here is that the detected evolutionary coupling (coevolution, compensatory mutations) results from evolutionary pressure, and is therefore indicative of direct contact.

Hyperglycemia related to GCK mutations results from defects in glucose-stimulated insulin secretion (2) and hepatic synthesis of glycogen from glucose (3).

The wild-type and Ser80 mutant E. coli enzymes all displayed similar abilities to cleave DNA, suggesting that quinolone resistance conferred by these mutations results from altered drug enzyme interactions rather than decreased enzyme activity.

Thus, despite generating a mutator effect itself, pol2-Y831A actually suppresses mutations resulting from loss of proofreading by Pol ε.

Most of the mutations resulted from dramatic population booms, they suggest.

Mutations resulting from translocations are assumed to be formed by misrejoining of two DNA double strand breaks (DSB), one within the gene and one on a different chromosome.

Applying the model to mutations of the hprt gene induced in G0 human lymphocyte cells by low-LET radiation, it is calculated that mutations resulting from translocations account for about 14% of the total mutations.

In addition to the nuclear germline and somatic mutations resulting from alteration in one or a small number of nucleotides, there are additional sources of genomic variation.