Sentence examples for mutations in targeted from inspiring English sources

Methods to alter the expression of and detect mutations in targeted genes involved are discussed.

Although gene transfer in peach is not practical, flowers can be fertilized with mutagenized pollen to generate M1 mutants; non-chimeric M1 populations would allow early screening for mutations in targeted genes by TILLING or next-generation sequencing.

The occurrence of escape mutations in targeted CD8 T cell epitopes is documented in HCV and has been shown to occur in epitopes restricted by a number of alleles.

(A) The c.451 C>T (R151X) mutations in targeted ES clones were confirmed by direct DNA sequencing.

Past descriptions of mechanisms of TKI resistance have been attributed to mutations in targeted kinases or compensatory activation of signaling pathways that circumvent the target.

Remarkably, CD8 + T cell inhibitory capacity was preserved and there were no new escape mutations in targeted Gag epitopes.

Thus, disruption of the Myo1 motor domain by kidney-disease-associated mutations resulted in targeting of Myo1 to eisosomes.

Subsequent studies showed that exposure to certain forms of energy, such as X-rays, could induce mutations in target cells that led to their malignant transformation.

A number of transgenic plants that may have mutations in target 1/2 in Nipponbare background were obtained.

Cas9-based editing technology should streamline the generation of animal and cell-line models, make the generation of activity-dead mutations in target validation routine, and enable the discovery of a new generation of targets across therapeutic areas.

One-tube LAMP-PCR-HY-RE-ELISA system was designed based on hot spot point mutations in target drug-resistant genes, using LAMP-PCR, hybridization, digestion with restriction endonuclease and colorimetric method of ELISA.