Sentence examples for mutations have found from inspiring English sources

Previous studies of patients with POLG1 mutations have found limited correlation between phenotype and genotype (38– 40).

Functional assays employing some of these mutations have found that the mutants encoded are dominant-negative and result in a drastic reduction in normal Cx43 function [ 4, 6].

Studies of families who segregate BRCA2 mutations have found that men who carry disease-associated mutations have an increased risk of prostate cancer, particularly early-onset disease.

These studies of TP53 mutations have found UVB-specific mutations, C-to-T transitions at dipyrimidine sequences and CC-to-TT tandem mutations as hallmarks of sunlight exposure leading to non-melanoma skin cancers [ 6].

Several studies in subjects with HFE gene mutations have found significant increases in red blood cell parameters including hemoglobin and mean corpuscular volume as compared with normal controls [ 8– 11].

Studies of the contribution of defective MMR to the development of urothelial carcinomas, assessed using MSI analysis, loss of MMR protein expression, and MMR gene mutations, have found a low frequency (<10%) of MMR defects in urothelial carcinomas of the urinary bladder [ 15], but have indicated a high frequency (15 45%) of MMR defects in UUC [ 16- 19].

Our detailed structural analysis of cancer associated somatic mutations has found several examples of mutations that could contribute to cancer progression through different mechanisms, all with high B-SIFT scores.

No matter where pastrami burgers began, and no matter their contemporary California mutations, they have found the widest acceptance in Salt Lake City, where the undisputed king of the category is Crown Burgers.

The functional consequences of the mutation we have found may help explain why the tumour arose.

Several studies of Rad51 among BRCA1 mutation carriers have found positive associations with cancer risk [ 28- 32].

The tangles researchers have found mutations in the gene called tau, which produces the material in the tangles.