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Exact(5)
First, mutations from two publically available web-based tools TBDreaMDB [ 18] and MUBII-TB-DB [ 19] were extracted.
In summary, we report here, for the first time, two novel ABCA4 mutations from two unrelated STGD patients of Indian origin.
To find mutations unique to each genotype, we generated data sets by intersecting mutations from two libraries and excluding mutations from the third.
We isolated dpy-17 mutations from two independently performed screens (S11 is from the first screen; S18, S19, and S23 are from the second screen), strongly suggesting that dpy-17 mutations suppress mua-3 lethality.
We addressed this question by engineering the candidate mutations from two clones, EvoClone2 and EvoClone9, into their ancestor and asking if this manipulation reproduced the behavior of these clones.
Similar(55)
A variant with combinatorial mutations from four individual CDRs achieved more than 19-fold affinity increase.
The ASD-ID list contained 827 genes harbouring de novo mutations from four ASD63,64,65,66 and two ID67,68 exome sequencing studies.
When this did not work, he resorted to the low-tech method of passing the virus (albeit one with three engineered mutations) from one ferret to another a number of times, giving it an opportunity to mutate naturally.
Mutations from five Nav1.1-related diseases are shown from intra-membrane, intracellular, and extracellular views.
Mapped mutations from nine Nav sodium channels to the Nav1.7 structure model are differentiated by distinct colors, Nav1.1 (A, blue), Nav1.2 (B, cyan), Nav1.3 (C, magenta), Nav1.4 (D, purple blue), Nav1.5 (E, pale cyan), Nav1.6 (F, orange), Nav1.7 (G, red), Nav1.8 (H, green), and Nav1.9 (I, salmon).
Real-time PCR, however, encounters technical difficulties when multiple mutations from one sample need to be detected simultaneously in a single tube.
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