Sentence examples for mutations form a from inspiring English sources

However, it has been shown that HCCs with activating CTNNB1 mutations form a group of HCCs, with a different histology, prognosis and genomic signature to those with inactivating biallelic AXIN1 mutations.

In this study, we re-examined the effect of VHL missense mutations to disrupt the formation of the VBC complex, and demonstrate that characteristic Type 2B VHL mutations form a low-abundance VBC complex which retains the ability to ubiquitylate HIF-1α.

Myelodysplastic syndromes with "multilineage dysplasia-associated mutations" form a distinct subset of MDS corresponding to disease categories in the WHO classification of "refractory cytopenia with multilineage dysplasia (RCMD)".

In some populations or ethnic groups, founder mutations form a sufficient proportion of the total to justify the adoption of specific molecular screening strategies.

In several populations or ethnic groups, distinctive founder mutations form a sufficient proportion of the total to justify the adoption of specific molecular screening strategies (Levy-Lahad et al, 1997; Peelen et al, 1997; Thorlacius et al, 1997; Moller et al, 2001).

GNAQ codon 209 mutations form an alternative route to MAP kinase activation [ 28].

These activating codon 209 mutations form an alternative route for MAP kinase activation and probably represent an initial stimulus for melanocytes to proliferate.

The secondary mutations form at a standard mutation rate, but are made more likely on selective medium by the increasing number of cells in the colony.

Using the median mutant frequency by the method of Drake (1991), this median frequency indicated that purR mutations form at a rate of 1.3 × 10−6 mutations per cell per division (Table 2).

Lineages DR53 and DR79 from Assam state share eleven specific coding region mutations and seven control region mutations to form a haplogroup, M62 (Fig. S1).

This resolvase, activated for recombination by mutations, forms a tetramer whose structure is substantially changed from that of a presynaptic complex between dimeric resolvase and the cleavage site DNA.