Sentence examples for mutations comprise a from inspiring English sources

KRAS mutations comprise a large fraction of driving mutations in a variety of tumors.

Our findings in Group 4 tumors with TERT mutations follow this pattern, while SHH tumors with TERT mutations comprise a prognostically favorable subgroup.

We also show that regenerant mutations comprise a distinctive molecular spectrum of base substitutions, insertions, and deletions that probably results from decreased DNA repair fidelity.

Grey curves in Fig. 7 show that beneficial mutations comprise a majority of fixations, but neutral and even mildly deleterious mutations can also become fixed, due to low population size.

The abnormal molecular phenotypes of these mutations comprise: (a) complete exon skipping, (b) reduced efficiency of splicing, (c) failure to remove introns (also termed intron retention or intron inclusion), or (d) cryptic splice site activation, which may define abnormal exon boundaries in transcripts using non-constitutive, proximate sequences, extending or truncating the exon.

Hyperactive or gain-of-function mutations comprise an area of functional analysis that is often overlooked in large-scale mutation analyses.

Second, mutations in regenerant plants might reflect somatic mutations that existed in the cells of the initial root explant prior to in vitro regeneration, with these somatic mutations comprising a molecular mutational spectrum differing from that of spontaneous "germline" mutations.

36 However, Hietpas et al. 37 report a clear bimodal DFE of mutations, comprising a set of nearly neutral mutations and a set of highly deleterious mutations; in fact, a closer look indicates that many site-directed mutagenesis studies reporting Γ-like DFE of mutations do actually see bimodal DFE if they include the set of lethal mutations.

Compound heterozygotes for CFTR mutations comprising a highly deleterious mutation on one allele (such as p.F508del) and a less severe mutation on the other allele (such as intron 8 5T) have long been known to display an increased risk of ICP (reviewed by Chen and Férec).

A mutation comprises a shift towards a new random value from the initial uniform [0 1] distribution.

A mutation comprises a change into a new random value from the uniform [0 1] distribution.