Sentence examples for mutations as it from inspiring English sources

This means that while SITS narrows the distribution of mutations by letting the less damaged cells live longer and removing highly mutated cells, the T-SCE widens the distribution of mutations as it both widens the distribution of cell longevities and at the same time recombination makes cells "forget" about their history of exposure to DNA damage.

Integration plasmids are often used in constructing chromosomal mutations, as it enables the alternation of genes at any location by integration or replacement.

Furthermore, it appears that such atypical networks can reliably be reached in relatively few generations, even when the range of variation available to selection is constrained to single point mutations as it was in these simulations.

The problem of distinguishing driver and passenger mutations is as acute for structural mutations as it is for point mutations [ 10- 13].

High resolution melting (HRM) analysis is an attractive screening method for the detection of both known and unknown mutations as it is rapid to set up and inexpensive to operate.

It has to be said that the splicing assay demonstrated that exon 17 inclusion was only partial for all of these mutations, as it was for the wild type exon.

Although multiple genes and signaling pathways have been implicated in renal cancer, VHL is the best characterized driver mutation, as it is mutated in the majority of sporadic ccRCC [ 10].

It was capable of accurately genotyping common Gaucher disease mutations as well as discovering a novel mutation and genetic polymorphism.

If they reversed these five mutations as well, the new receptor behaved like an old one.

The TDT analysis detected the protective role of the HbS mutation as it was under-transmitted to CM children (P = 0.036) (Table 4).

We chose the F595 to Ala mutation as it induced a large decrease in the constitutive activity of V617F (Figure 2A).