Sentence examples for mutations are discovered from inspiring English sources

As more Y chromosome mutations are discovered, he says, researchers will be able to paint an ever higher resolution picture of human prehistory--the when, where, and Y of human evolution.

Indeed, the three primary mutations are prerequisites for LHON, and many other rare LHON mutations are discovered continuously (c.f. http://www.mitomap.org/MITOMAP/MutationsLHON).

However, most pro-longevity mutations are discovered by systematic gene deletion or RNA interference screens, which mainly reveal abolished or diminished gene functions [ 1].

If this FALS-SALS percentage ratio were to remain the same when 100% of FALS-causing mutations are discovered, by extrapolation only 16% of SALS patients will harbour ALS-causing mutations.

Although many somatic mutations are discovered, a small fraction of mutations promote cancer progress (driver genes that drive tumor evolution, about <1%) and majority of mutations are likely to be "passengers" which have no effects on tumor cell selection [ 3– 5].

More recently, massively parallel and deep sequencing of the cancer genome using next-generation sequencing (NGS) technologies has vastly increased the rate at which clinically significant and therapeutically targetable mutations are discovered (Ross and Cronin, 2011; Dutton-Regester and Hayward, 2012; Li et al, 2013; Martelli et al, 2013; Mwenifumbo and Marra, 2013; Workman et al, 2013).

Soon thereafter, the SDHC gene was found to be mutated in familial HNPGLs (PGL3; Niemann & Muller 2000) and SDHB mutations were discovered in familial PPGLs (PGL4; Astuti et al. 2001 b ).

Further, the diagnosis of primary haemochromatosis has improved since various associated genetic mutations were discovered some years ago.

Ten years ago, α-synuclein mutations were discovered as the first genetic cause of Parkinson's disease (PD).

Some amino acid mutations were discovered to be crucial for virus virulence (Yang et al., 2014), but how they affect the viral virulence remained unclear.

Since these C9orf72 mutations were discovered in 2011, some researchers have speculated that the repeats interrupt production of the gene's normal protein, which serves some as-yet unknown, but vital function in motor neurons or other brain cells.