mutational status in

USAGE SUMMARY

The phrase "mutational status in" is correct and usable in written English.
It can be used in contexts related to genetics, biology, or medical research when discussing the genetic variations or mutations present in a specific sample or organism. Example: "The study focused on the mutational status in tumor samples to determine the effectiveness of targeted therapies."

✓ Grammatically correct

Science

Academia

Human-verified examples from authoritative sources

Exact Expressions

59 human-written examples

Different mutational status in different studies; possibly a TP53-mutated subclone exists.

Breast Cancer Research

To date, only one study investigating APC mutational status in four CNS PNET tumours has been reported, in which no mutations were found (Koch et al, 2001).

British Journal of Cancer

Our results indicate that fragment length analysis should not be used in isolation, and that direct sequencing is required to evaluate CEBPA gene mutational status in acute myeloid leukemia.

Stanford University

In the last decades, there have been several efforts to clarify the role of BRCA mutational status in women with advanced ovarian cancer, demonstrating its role in cancer development, as well as the prognostic significance of BRCA genotype.

American Journal of Obstetrics and Gynecology

In the present study, we have evaluated PIK3CA mutational status in a series of 410 Middle Eastern CRC and 13 colon cell lines to study the prevalence of PIK3CA mutations in MSI cases, PTEN expression in CRC and possibility of therapeutic targeting of this set of patients.

Nature

Moreover, since approximately 50% of NSCLC patients treated with TKIs ultimately develop secondary mutations in the EGFR TK domain in tumors and consequently resistance to erlotinib treatment, PET should also afford longitudinal monitoring of EGFR mutational status in tumors.

EJNMMI Research

All of these findings confirm that analysis of KRAS mutational status in the primary tumor is an adequate surrogate marker of KRAS mutational status in metastases.

Plosone

In these patients, KRAS mutational status in the primary tumor was previously analysed for clinical purposes prior to cetuximab administration.

Plosone

We also aimed to assess an association between BRAFV600E mutational status in metastatic melanoma patients and response to sorafenib therapy.

Plosone

We note that miR-34a, previously shown to regulate TP53 [14], is not observed to be differentially expressed in comparing TP53 mutational status in this cohort (Table S3).

Plosone

Recent data have demonstrated an association between KRAS mutational status in the primary tumor and resistance to cetuximab and panitumumab in patients with metastatic CRC [13], [14].

Plosone

Expert writing Tips

Best practice

When discussing the presence or absence of specific mutations, always specify the gene or region being analyzed to provide clarity and avoid ambiguity.

Common error

Avoid assuming that the "mutational status" observed in a single sample accurately represents the entire organism or tumor. Account for potential variations across different tissues or time points.

Linguistic Context

The phrase "mutational status in" functions as a noun phrase followed by a preposition, typically acting as an adjective modifying another noun. It describes the condition of having specific mutations within a given context, as supported by examples found by Ludwig.

Expression frequency: Very common

Frequent in

Science

90%

Academia

8%

Formal & Business

1%

Less common in

News & Media

1%

Encyclopedias

0%

Wiki

0%

Ludwig's WRAP-UP

The phrase "mutational status in" is a grammatically correct and very common term primarily used in scientific and academic contexts. As Ludwig AI confirms, it effectively conveys information about the presence, absence, or characteristics of genetic mutations within a specific context. Alternative phrases like "mutation profile in" can be used to add variety to your writing. When using this phrase, specify the gene or region being analyzed and be cautious about extrapolating findings from a single sample to an entire organism.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

mutation profile in

Replaces "mutational status" with "mutation profile", emphasizing a comprehensive overview of mutations.

genetic alteration in

Uses "genetic alteration" instead of "mutational status", broadening the scope to include any change in the genetic material.

mutation landscape in

Substitutes "mutational status" with "mutation landscape", offering a more visual and comprehensive representation of mutations.

gene mutation in

Focuses specifically on gene mutations, narrowing the scope from broader mutational statuses.

mutated gene in

Highlights the presence of a "mutated gene" rather than the overall status.

mutation presence in

Emphasizes the existence of mutations within a particular context.

mutational profile within

Uses "mutational profile within" to specify a more confined area or sample.

gene variant in

Replaces "mutation" with "gene variant", focusing on variations in the genetic sequence.

genetic mutation in

Combines "genetic" and "mutation" to emphasize the genetic origin of the mutation.

altered gene in

Uses "altered gene" to describe the state of the gene, rather than the process of mutation.

FAQs

How is "mutational status in" typically assessed?

The "mutational status in" a sample is commonly determined through methods such as DNA sequencing, polymerase chain reaction (PCR), and other molecular diagnostic techniques. These methods identify the presence or absence of specific genetic mutations.

What is the significance of "mutational status in" cancer research?

The "mutational status in" cancer cells can influence disease progression, treatment response, and prognosis. Identifying specific mutations helps in selecting targeted therapies and predicting patient outcomes.

What factors can influence the "mutational status in" a population?

Factors such as environmental exposures, genetic predispositions, and lifestyle choices can contribute to variations in the "mutational status in" different individuals or populations.

Are there alternatives to "mutational status in"?

Yes, depending on the context, alternatives such as "mutation profile in", "genetic alteration in", or "mutation landscape in" can be used to describe the presence and characteristics of mutations.