mutation profile in

USAGE SUMMARY

The phrase "mutation profile in" is correct and usable in written English.
It can be used in contexts related to genetics, biology, or medical research when discussing the specific characteristics of mutations within a particular sample or organism. Example: "The mutation profile in the tumor samples revealed several key genetic alterations that could inform treatment options."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

13 human-written examples

Taffon, S, Genovese, D, Blasi, M, Pierotti, P, Degli Esposti, A, Catone, S, Chionne, P, Pulimanti, B, Candido, A, Dettori, S, Tosti, ME, Argentini, C, Mazzotta, F, and Rapicetta, M. "HBV whole-genome mutation profile in HIV-1/HBV coinfected patients in a long-term follow-up study". Infection 42, no. 4 (August 2014): 675-687.

Duke University

The mutation profile in the TP53 gene can indicate the potential cause of the mutation.

British Journal of Cancer

This underscores that the gene expression data is more informative than patient mutation profile in locating ovarian cancer genes.

BMC Genomics

However, a particular characteristic of TP53 mutation profile in tumours from high-incidence areas is a large proportion of transitions at CpG sites.

Bioscience Reports

We found that C→T and C→A were the predominant types of postzygotic mutations, similar to the somatic mutation profile in tumor tissues.

Cell Research

When taking into account the mutation profile in our analysis, lower CLu also proved to predict better responses in both groups.

British Journal of Cancer

Human-verified similar examples from authoritative sources

Similar Expressions

47 human-written examples

Kim SY, Im K, Park SN et al. CALR, JAK2, and MPL mutation profiles in patients with four different subtypes of myeloproliferative neoplasms: primary myelofibrosis, essential thrombocythemia, polycythemia vera, and myeloproliferative neoplasm, unclassifiable.

Nature

Mutation profiling in mice provides direct evidence that somatic AR variants are selected by therapy, a finding validated in human metastases from distinct treatment groups.

Molecular and Cellular Endocrinology

We report the implementation of a genotyping and validation algorithm that enables robust tumor mutation profiling in the clinical setting.

Plosone

To facilitate cancer gene mutation profiling in clinical tumor specimens, we developed OncoMap, a panel of genotyping assays that assessed 396 unique mutations in 33 cancer genes.

Plosone

In summary, this study represents the first large-scale application of the OncoMap platform for tumor mutation profiling in the clinical and archival setting.

Plosone

Expert writing Tips

Best practice

When describing the "mutation profile in" a sample, be specific about the type of mutations (e.g., somatic, germline) and the genomic region being analyzed. This ensures clarity and avoids ambiguity.

Common error

Avoid using "mutation profile" when you actually mean gene expression profile. A mutation profile describes changes in the DNA sequence, whereas a gene expression profile reflects the levels of mRNA transcripts produced by different genes.

Linguistic Context

The phrase "mutation profile in" functions as a noun phrase, typically serving as the subject or object of a sentence. It identifies and describes the pattern of genetic mutations observed within a specific context. Ludwig's examples show the phrase being used to specify the mutations present in tumors, patients, or populations.

Expression frequency: Uncommon

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

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Academia

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Ludwig's WRAP-UP

The phrase "mutation profile in" is a noun phrase used to describe the specific pattern and types of genetic mutations within a particular context. As Ludwig AI states, it is grammatically correct and primarily used in scientific and academic fields. The phrase's purpose is to provide detailed information about the mutations present in a sample, organism, or population. It is crucial to maintain specificity when describing the mutation profile and avoid confusion with other related terms like gene expression profile.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

mutation signature within

Focuses on characteristic patterns or signatures of mutations.

genetic mutation landscape in

Emphasizes the broad view of mutations across the genome.

mutational spectrum within

Highlights the range and distribution of different types of mutations.

mutation pattern observed in

Focuses on recurring patterns of mutations.

genomic alteration profile in

Broader term encompassing all types of genomic changes, not just mutations.

mutational background within

Highlights the pre-existing mutational status.

mutation load within

Highlights quantity of mutations instead of quality or pattern.

mutation status within

Indicates presence or absence of specific mutations.

genetic variant profile in

Emphasis on genetic variants, which are a broader category including mutations.

mutation fingerprint within

Emphasizes the unique identifying characteristics of mutations.

FAQs

What does "mutation profile in" mean in genetics?

In genetics, "mutation profile in" refers to the specific pattern and types of genetic mutations observed within a particular sample, organism, or population. It includes information about which genes are mutated, the type of mutations (e.g., insertions, deletions, substitutions), and their frequencies.

How is a "mutation profile in" typically determined?

A "mutation profile in" is usually determined through methods like exome sequencing or other targeted sequencing approaches. These technologies allow scientists to identify and characterize genetic variations in a sample by comparing it to a reference genome.

What is the significance of analyzing the "mutation profile in" a tumor?

Analyzing the "mutation profile in" a tumor can provide insights into its development, progression, and potential response to therapy. Identifying specific mutations can help oncologists select targeted treatments that are more likely to be effective. You may find similar phrases to "mutation profile in" such as "mutation signature within".

Is there a difference between "mutation profile in" and "mutation profiles in"?

The phrase "mutation profile in" refers to a singular instance while "mutation profiles in" refers to multiple instances. For example, "mutation profile in" refers to the mutation profile in one patient whereas "mutation profiles in" refers to the mutation profiles in multiple patients.