Sentence examples for mutation was successfully from inspiring English sources

Repair of a splicing defect of β-globin pre-mRNA harboring hemoglobin E (HbE) mutation was successfully accomplished in erythroid cells from patients with β-thalassemia/HbE disorder by a synthetic splice-switching oligonucleotide (SSO).

One newly designed and easily synthesized phosphorylated BChE nonapeptide with one Gly-to-Ala mutation was successfully reported to serve as internal standard instead of traditional isotopically labeled BChE nonapeptide.

A control sample with this mutation was successfully analysed, confirming the negative result of this mutation in the described series.

Southern blot analysis confirmed that the desired mutation was successfully introduced (Fig. 1B, left), and genotypes of offspring were routinely analyzed by PCR (Fig. 1B, right).

Thus, in this in-vitro model experiment, the BRAF mutation was successfully detected in individual melanoma cells isolated from peripheral blood.

A case report has previously shown that a patient with NSHPT bearing an R185Q mutation was successfully treated with cinacalcet, an FDA approved positive allosteric modulator of CaSR [45].

Based on previous experience [ 29], two patients of our cohort with trisomy 21 mosaic and GATA1 mutation were successfully treated with a reduced intensity regimen for DS-AMKL paccordingaccording to treatment recommendation of the ML-DS 2006 registry).

In addition, the total of 14, 24, 37 and 27 mutations were successfully chosen at 1, 3, 10 and 20% of MnCl2.

Collectively, Southern and Western blot analysis indicated that the intended mutations were successfully introduced into the HSV-2 ICP0 gene.

Once the mutations were successfully incorporated, the 1.7 kB hCE1 cDNA was ligated into pCIneo for mammalian cell expression (Promega, Madison, WI).

KRAS and BRAF mutations were successfully evaluated in 525 and 524 cases, respectively.