Sentence examples for mutation status have from inspiring English sources

Gene expression, miRNA expression, ER status, HER2 status and TP53 mutation status have been described before (Enerly et al, 2011).

Epithelial growth factor receptor (EGFR) and KRAS mutation status have been reported as predictive markers of tumour response to EGFR inhibitors.

Recently, MMR status, KRAS and BRAF mutation status have attracted remarkable attention due to their potential prognostic and predictive role in colorectal carcinomas [ 10- 12].

The features that are most predictive of mutation status when all are considered together have been identified, and the extent to which each feature is predictive of mutation status have been quantified.

Recent analyses (Bell et al, 2005) of phase II and III trials for EGFR-TKI, in which patients were not selected based on their mutation status, have suggested that EGFR mutations are correlated with response to therapy but are not correlated with overall survival (OS).

The cost-effectiveness of first-line maintenance erlotinib in the overall SATURN population has been assessed and published recently, but analyses according to EGFR mutation status have not been performed yet, which was the rationale for assessing the cost-effectiveness of first-line maintenance erlotinib specifically in EGFR wild-type metastatic NSCLC.

More recently, a mutated Kras-specific signature that can be used to classify human and mouse lung tumours on the basis of their KRAS mutation status has been identified by comparing KRAS-mutated human cancer cells to mouse somatic cells containing knocked-in mutant Kras [275].

KRAS mutation status has been reported to be a predictive marker of tumor response to epidermal growth factor receptor (EGFR) inhibitors.

TP53 mutation status has been shown to be one of the strongest single molecular prognostic markers in breast cancer.

The RPS19 mutation status has not been predictive of response in any series.

For all tumor samples the mtDNA mutation status has been previously determined [ 7].