Sentence examples for mutation stabilizes the from inspiring English sources

We conclude that while the V67L mutation stabilizes the global structure, cooperative dynamics of all intein regions appear more important for intein function than high stability.

Lastly, we show that the rpn1-D517A mutation stabilizes the Ddi1 substrate, Ufo1.

In contrast, the comparison of the wild-type peptide and the A391E mutant peptide showed that the A391E mutation stabilizes the TM dimer.

This suggests that the alanine mutation stabilizes the closed state in Kv channels, instead of destabilizing it as in mouse TRPC3, hinting that the mechanism may not be conserved.

The most striking feature of the thermograms is that, although it is clear that each mutation stabilizes the protein, heat and cold denaturation are affected in a strikingly different way.

Further, the N2C/D282C mutation stabilized the unliganded opsin in detergent micelles.

Together, both effects indicate that the G137I mutation stabilized the C-type gate.

This supported our previous observation that the C155 to A155 mutation stabilized the K-turn motif formation between C-box anD-box3x3 (fig. 2 B and C) and is consistent with the accumulation of L-Snord115 as observed in northern blots (fig. 2 B).

However, the reason why a particular mutation, or combination of mutations, stabilizes the receptor is not always evident from a static crystal structure.

The Y227A5.58 and V230A5.61 mutations stabilize the ionic lock between R1393.50 on transmembrane helix3 and E2856.30 on transmembrane helix6.

Characterization of several of designs and point mutants revealed that in all cases, the mutations stabilize the interface by 10- to 1000-fold relatove to wild type BLIP.