Sentence examples for mutation rate calculation from inspiring English sources

To do so, the user should use an advanced mutation rate calculation packages to explore different models such as Salvador (Zheng 2008b).

To quantify the proportion of heteroplasmy in samples that appeared to be relevant to mutation rate calculation, a PCR using primers L-MT3120 H-MT38893889 was performed.

However, the observation of substantial copy number variation in C. elegans [ 53] suggests that it is probably most appropriate to apply a mutation rate calculation that includes indels, as we have done.

Band-sharing tends to reflect mutation rate (higher mutation rates drive higher diversity and hence lower band-sharing) while band number will influence the mutation rate calculation (see above).

To our knowledge there was so far a single web-tool available for mutation rate calculation (Hall et al. 2009) but this tool does not allow to consider deviations from Luria Delbrück or to estimate the goodness of fit with the model.

Mutation rate calculations assumed each MA line underwent 2500 generations.

Mutations mapped to these two positionally uncertain C. briggsae sequence types were used for total mutation rate calculations but omitted from analyses involving chromosome domain and coding region analyses.

To compensate for the possibility of our synonymous mutation rate calculations being affected by the overall level of sequence conservation between human and mouse, or by specific features of 5' and 3' UTR sequences, we used sequences immediately adjacent to, and of the same length as, the ORFs to generate additional control data.

Mutation frequency (MF) and mutation rate (MR) calculations were performed essentially as described (Eshleman et al, 1995).

For the purpose of our estimate, we derived a mutation rate using a simplified calculation with the homozygous mutants.

This method of frequency-based analysis typically requires an estimation of the non-synonymous background mutation rate (nsBMR) followed by calculation of the statistical likelihood of observing a certain number of mutations based on the nsBMR.