Sentence examples for mutation pattern is from inspiring English sources

Hence, because passenger mutations vastly outnumber driver mutations, in the absence of selection the overall SBS mutation pattern is believed to capture the composite history of the mutational processes that acted upon the tumor cells.

Such relationships were observed in the many of the sequences that showed mutant genotypes, and information of this source is important when a detected mutation pattern is being interpreted.

The mutation pattern is summarized in Figure  2B.

The mutation pattern is very likely more complex (e.g., Amos 2010).

We believe that a better way to explore the real mutation pattern is to directly capture mutations during bacterial replication.

Therefore, it seems that the mutation pattern is a major player in determining frame-shift stop-codon frequencies, while selection does not seem to play a major role.

This mutation pattern was consistent with a colonic rather than a pancreatic carcinoma [ 45].

Most of the haplotypes were singletons; this mutation pattern was more common in colonies of shallow habitats.

The TP53 mutation pattern was also incompatible with a simple genetic progression model in 2 out of 7 patients.

Apart from six tumors with second hits, two tumors showed LOH (Fig. 2b) in which the heterozygous mutation pattern was completely replaced by a hemizygous mutation pattern.

The overall spontaneous mutation level and the associated composite mutation pattern are therefore expected to be similar from person to person within the human population.