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Exact(8)
Investigation of mutation pattern and distribution along the hematopoietic tree may influence the therapeutic decision for targeted therapy.
However, the number of BHD cases analyzed in their study was small, and we need an analysis of more cases to clarify the relationship between the gene mutation pattern and clinical symptoms.
To elucidate the frequency of doublets and the distinct mutation pattern and spectrum in the EGFR gene, the epidemiology of doublet mutations in lung cancer is analyzed and compared to that of doublets in the TP53 gene.
To most effectively use microsatellites for divergence estimation, we need to understand their mutation pattern and the factors that affect their mutation rate.
The highest scoring features are GARP score for gene essentiality, RMA intensity for mRNA expression, row chromosomal copy number for DNA copy number, mutation occurrence for somatic mutation pattern and closeness centrality for network-topological property.
Fu (2013) extended the previous inference framework (Gao et al. 2011) with a new method for approximating the probability of a mutation pattern and a refined coalescent algorithm for simulating sample genealogies which are necessary for deriving coefficients used in the analysis.
Similar(52)
Correlations between international variation in colorectal cancer-associated mutation patterns and food availabilities could highlight the influence of foods on colorectal mutagenesis.
Mutation patterns and other categorical count distributions were tested for significant differences by the Fisher's Exact Test or unordered R×C contingency tables using the "Fisher-Freeman-Halton" test implemented by the StatXact statistical analysis software package (CYTEL Software Corporation, Cambridge, MA).
CCLE is therefore an ideal resource to explore mutation patterns and frequencies in a large scale.
The neutral explanation hypothesizes that bias exists because of nonrandom mutation patterns and genetic drift.
We used DNASP 5.0 to assess the mutation patterns and Fst between the tested populations (Librado and Rozas 2009).
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