Sentence examples for mutation profiles and from inspiring English sources

Because of the tremendous diversity and complexity of cancer gene mutations, cancers even the same type of cancers show very different mutation profiles and few common patterns behind these data have been identified.

Type I and II endometrial cancers have different mutation profiles and precursor lesions (Sherman, 2000; Fadare and Zheng, 2008).

These projects seek to find correlations between mutation profiles and clinical outcomes, identify mutations driving cancer progression and identify targets for novel therapeutic developments.

These data, assessed from the perspective of individual patients, provide one of the first glimpses of personal mutation profiles and establish a foundation to elucidate the disease significance of these variants in future next-generation sequencing analyses of PIBD patients.

Pathway analysis was performed to examine the association between mutation profiles and core canonical pathways in Asian OTSCC, using either the MSigDB pathways database [ 62] or compared with manually curated cancer-related pathways [ 63, 64].

We further integrated cancer cell line mutation profiles and drug pharmacological data from the Cancer Cell Line Encyclopedia (CCLE) onto protein pocket regions in order to identify putative biomarkers for anticancer drug responses.

This suggests a high proportion of mutagenesis occurs in the first 14 days post-infection, with subsequent rare events of superinfection and selective pressure shaping the mutation profile and the eventual clonal outgrowth of late-stage lymphomas.

Mutation profile and predicted genotypic resistance were analyzed by comparison to the Stanford HIV Drug Resistance Database (hivdb.stanford.edu).edu

We did not find any correlation between the gene mutation profile and NTM infection.

A list of the 31 proteins from artificial sources, together with their mutation profile and corresponding GI is provided in Additional file 1: Table S2.

Thus, for each case, only the determination of all potential mutations and the reconstitution of the mutation profile and clonal evolution will help understand the pathophysiology of the disease.